Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23771876 | 0.96 | TDP1 (0.54) | TDP1CYP19A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9504297 | 0.90 | TDP1 (0.68) | TDP1CYP19A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28184406 | 0.85 | TDP1 (0.57) | TDP1CYP19A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19614904 | 0.84 | TDP1 (0.41) | TDP1CYP19A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL17435832 | 0.82 | TDP1 (0.46) | TDP1ALDH1A1KDM4EHSD17B10MAPK1 | |
| SCHEMBL27470862 | 0.82 | TDP1 (0.64) | TDP1CYP19A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14521446 | 0.81 | TSHR (0.45) | TDP1ALDH1A1HSD17B10MAPK1KMT2A | |
| SCHEMBL2192211 | 0.81 | TSHR (0.45) | TDP1ALDH1A1MAPK1KMT2ATSHR | |
| SCHEMBL27970282 | 0.79 | TDP1 (0.44) | TDP1ALDH1A1KDM4EHSD17B10MAPK1 | |
| SCHEMBL28250371 | 0.79 | TSHR (0.43) | TDP1ALDH1A1MAPK1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412449-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element using same | 日产化学株式会社 | 2021-09-17 | — | — | CN | disclosed |
| US-8084643-B2 | Nitrogen-containing esters of the secondary alcohol group of florfenicol and of its analogs,including salts; veterinary medicine; nonhydrolyzing as needed to maintain the prodrug in aqueous solution in the subjects system until appropriate; cattle drinking water; bovine respiratory disease | INTERVET INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | PFAS, ADH5, SI | TDP1 860/4885CYP19A1 509/4885ALDH1A1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.