Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 4/20 | 0.41 |
| ▸ | FNTB | P49356 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4889157 | 0.96 | CXCR4 (0.46) | CXCR4HDAC1HDAC6FNTAFNTB | |
| SCHEMBL5241314 | 0.89 | CXCR4 (0.41) | CXCR4HDAC1HDAC6FNTAFNTB | |
| SCHEMBL4885774 | 0.88 | CXCR4 (0.47) | CXCR4HDAC1HDAC6FNTAFNTB | |
| Trifluoroacetic Acid SCHEMBL4889301 | 0.84 | CXCR4 (0.44) | CXCR4HDAC1HDAC6FNTAFNTB | |
| Trifluoroacetic Acid SCHEMBL5269798 | 0.80 | CXCR4 (0.40) | CXCR4HDAC1HDAC6ADORA2A | |
| SCHEMBL3996320 | 0.79 | CXCR4 (0.52) | CXCR4HDAC1HDAC6FNTAFNTB | |
| SCHEMBL20482776 | 0.77 | CXCR4 (0.46) | CXCR4HDAC1HDAC6FNTAFNTB | |
| SCHEMBL21744230 | 0.77 | CXCR4 (0.46) | CXCR4HDAC1HDAC6FNTAFNTB | |
| SCHEMBL20482775 | 0.77 | CXCR4 (0.46) | CXCR4HDAC1HDAC6FNTAFNTB | |
| SCHEMBL30380547 | 0.77 | CXCR4 (0.46) | CXCR4HDAC1HDAC6FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045537-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-02-21 | — | — | US | disclosed |
| EP-1789045-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006023400-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045537-A1 | Chemical Compounds | CCR5, CXCR4, CXCR3 | CXCR4 2/4885HDAC1 844/4885HDAC6 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.