Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.52 |
| ▸ | CTSK | P43235 | 13/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15968308 | 0.85 | CTSS (0.51) | CTSSCTSKCTSLCTSB | |
| SCHEMBL22498643 | 0.84 | CTSS (0.52) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL22498641 | 0.84 | CTSS (0.52) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL9226653 | 0.82 | CTSS (0.50) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL12954645 | 0.82 | CTSS (0.51) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL15512333 | 0.81 | CTSS (0.56) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL29844099 | 0.81 | CAPN1 (0.52) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL15512308 | 0.81 | CTSS (0.56) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL17087706 | 0.81 | CAPN1 (0.46) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL14029765 | 0.79 | CTSS (0.53) | CTSSCTSKCTSLCTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AICURIS GMBH & CO. KG (DE) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | ARG1, HRH3, H1-0 | CTSS 1049/4885CTSK 1658/4885CTSL 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.