SCHEMBL48861

SCHEMBL48861

O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.71
HSD17B10 Q99714 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
CA1 P00915 3/20 0.60
CA2 P00918 3/20 0.60
CA12 O43570 2/20 0.60
CA9 Q16790 2/20 0.60
MMP2 P08253 1/20 0.50
MMP7 P09237 1/20 0.50
MMP14 P50281 1/20 0.50
GAA P10253 1/20 0.48
PTGS2 P35354 1/20 0.48
PKM P14618 1/20 0.48
PARL Q9H300 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21993320 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1CA1CA2
Hydrochloric Acid SCHEMBL5174554 0.98 ALDH1A1 (0.68) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL5891023 0.89 ALDH1A1 (0.60) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL150162 0.89 ALDH1A1 (0.60) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL18424824 0.89 PTGS2 (0.64) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL9539212 0.88 ALDH1A1 (0.56) ALDH1A1HSD17B10TDP1CA1CA2
Water SCHEMBL7024182 0.87 ALDH1A1 (0.57) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL10704793 0.84 TDP1 (1.00) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL17223 0.84 TDP1 (1.00) ALDH1A1HSD17B10TDP1CA1CA2
Benzene SCHEMBL4292987 0.84 TDP1 (1.00) ALDH1A1HSD17B10TDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 US claimed
EP-4720316-A2 NON-VIRAL CELL ENGINEERING Arsenal Biosciences, Inc. (US) 2026-04-08 EP claimed
EP-4692062-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME Amorepacific Corporation (KR) 2026-02-11 EP claimed
US-20250115871-A1 METHODS TO IMPROVE ENDURING HEMATOPOIETIC STEM CELL TRANSPLANTATION TRAILHEAD BIOSYSTEMS INC. 2025-04-10 US claimed
WO-2024259376-A2 NON-VIRAL CELL ENGINEERING ARSENAL BIOSCIENCES, INC. (US) 2024-12-19 WO claimed
EP-4441205-A1 METHODS AND COMPOSITIONS FOR MAINTAINING AND EXPANDING HEMATOPOIETIC STEM CELLS Trailhead Biosystems Inc. (US) 2024-10-09 EP claimed
WO-2024205303-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME (주)아모레퍼시픽 2024-10-03 WO claimed
CN-118302519-A Methods and compositions for maintaining and expanding hematopoietic stem cells 特雷尔赫德生物系统股份有限公司 2024-07-05 CN claimed
US-20230310479-A1 LOW DOSE ADJUVANT EPIGENETIC CANCER THERAPY UNIV JOHNS HOPKINS (US) 2023-10-05 US claimed
WO-2023143608-A1 COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF 上海复东生物医药有限责任公司 2023-08-03 WO claimed
CN-106188950-A A kind of pvc sheath compensating cable 张翔 2016-12-07 CN claimed
US-20140364566-A1 SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2014-12-11 US claimed
WO-2014042603-A1 ENHANCED THERMAL STABILITY POLYALKYLENE CARBONATE COMPOSITION AND A PREPARATION METHOD THEREOF PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2014-03-20 WO claimed
WO-2012160452-A1 TWO-PART POLYMERISABLE COMPOSITIONS HENKEL IRELAND LIMITED (IE) 2012-11-29 WO claimed
EP-2385831-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT The UAB Research Foundation (US) 2011-11-16 EP claimed
US-20110254866-A1 INFORMATION PROCESSING APPARATUS, METHOD AND PROGRAM THEREFORE SONY CORPORATION (JP) 2011-10-20 US claimed
WO-2010123591-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT THE UAB RESEARCH FOUNDATION (US) 2010-10-28 WO claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
EP-1025081-B1 S-(4-BIPHENYL)-THIOSULPHURIC ACIDS AND THEIR SALTS, METHOD FOR PRODUCING THE SAME AND METHOD FOR PRODUCING 4-MERCAPTOBIPHENYLS BAYER AG (DE) 2002-03-13 EP claimed
CN-1277603-A S-(4-Biphenyl)-thiosulphuric acids and their salts method for producing the same and method for producing 4-mercaptobiphenyls BAYER AG (DE) 2000-12-20 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES WNT3A, GSK3B, GSK3A ALDH1A1 1732/4885HSD17B10 75/4885TDP1 4119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.