Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17160801 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL13486844 | 0.93 | MAPT (0.48) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL13486846 | 0.93 | MAPT (0.48) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL142069 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL13917807 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL12298937 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL6312542 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL9331190 | 0.81 | NOS3 (0.54) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| SCHEMBL9331652 | 0.81 | NOS3 (0.54) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| SCHEMBL40655 | 0.81 | NOS3 (0.54) | ALDH1A1TSHRALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3254709-B1 | TWO COMPONENT POLYMETHACRYLATE BONE CEMENT IN PASTE FORM | HERAEUS MEDICAL GMBH (DE) | 2020-02-26 | — | — | EP | claimed |
| US-20170348457-A1 | PASTY TWO-COMPONENT POLYMETHACRYLATE BONE CEMENT | HERAEUS MEDICAL GMBH (DE) | 2017-12-07 | — | — | US | claimed |
| US-20080041520-A1 | Adhesive and method for binding artificial plastic teeth | DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) | 2008-02-21 | — | — | US | claimed |
| US-5908960-A | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-01 | — | — | US | claimed |
| EP-4312945-A1 | SELF-ADHESIVE DENTAL MATERIAL | Kulzer GmbH (DE) | 2024-02-07 | — | — | EP | disclosed |
| EP-4312947-A1 | SELF-ADHESIVE FISSURE SEALANT | Kulzer GmbH (DE) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022207877-A1 | SELF-ADHESIVE DENTAL MATERIAL | KULZER GMBH (DE) | 2022-10-06 | — | — | WO | disclosed |
| US-11414436-B2 | Non-coordinating anion type activators containing cation having large alkyl groups | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-08-16 | — | — | US | disclosed |
| WO-2022094420-A1 | SELECTIVE TRANSITION METAL CATALYZED DEUTERIUM INCORPORATION INTO ALKYNE AND ALKENE FUNCTIONALITIES | MARQUETTE UNIVERSITY (US) | 2022-05-05 | — | — | WO | disclosed |
| CN-112055579-A | One-component dental adhesive composition for fixing dental composite material | 3M创新有限公司 | 2020-12-08 | — | — | CN | disclosed |
| EP-3254709-B1 | TWO COMPONENT POLYMETHACRYLATE BONE CEMENT IN PASTE FORM | HERAEUS MEDICAL GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-20190330139-A1 | Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-10-31 | — | — | US | disclosed |
| US-5908960-A | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-01 | — | — | US | disclosed |
| EP-0916637-A1 | PROCESS FOR PREPARATING OPTICALLY ACTIVE COMPOUNDS | Japan Science and Technology Corporation (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0881210-A1 | Process for the production of N,N-dialkylaminophenyl alkanols | Ciba SC Holding AG (CH) | 1998-12-02 | — | — | EP | disclosed |
| US-5028638-A | Hybrid plastic filling material | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0382033-A2 | Hybrid synthetic resin filling materials | BAYER AG (DE) | 1990-08-16 | — | — | EP | disclosed |
| EP-0148401-B1 | AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR RADICALLY POLYMERISABLE COMPOSITIONS | BAYER AG (DE) | 1987-04-01 | — | — | EP | disclosed |
| US-4628112-A | Amines, processes for their preparation and their use in compositions which can undergo free radical polymerization | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | disclosed |
| EP-0148401-A1 | Amines, process for their preparation and their use for radically polymerisable compositions | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414436-B2 | Non-coordinating anion type activators containing cation having large alkyl groups | KCNK10, KCNK4, HCN4 | ALDH1A1 2589/4885TSHR 3730/4885ALOX15 907/4885 |
| US-20190330139-A1 | Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups | KCNK10, KCNK4, HCN4 | ALDH1A1 2572/4885TSHR 3717/4885ALOX15 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.