Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | OGG1 | O15527 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903094 | 1.00 | MAPT (0.50) | MAPTALDH1A1OGG1CYP1A2CYP3A4 | |
| SCHEMBL4886109 | 1.00 | MAPT (0.50) | MAPTALDH1A1OGG1CYP1A2CYP3A4 | |
| SCHEMBL4903099 | 1.00 | MAPT (0.50) | MAPTALDH1A1OGG1CYP1A2CYP3A4 | |
| SCHEMBL4874999 | 0.93 | MAPT (0.47) | MAPTALDH1A1OGG1CYP1A2CYP3A4 | |
| SCHEMBL4875002 | 0.93 | MAPT (0.47) | MAPTALDH1A1OGG1CYP1A2CYP3A4 | |
| SCHEMBL2907122 | 0.92 | MAPT (0.53) | MAPTALDH1A1CYP1A2CYP3A4RAB9A | |
| SCHEMBL2907123 | 0.92 | MAPT (0.53) | MAPTALDH1A1CYP1A2CYP3A4RAB9A | |
| SCHEMBL4912706 | 0.90 | CYP1A2 (0.53) | MAPTALDH1A1OGG1CYP1A2CYP3A4 | |
| SCHEMBL4912712 | 0.90 | CYP1A2 (0.53) | MAPTALDH1A1OGG1CYP1A2CYP3A4 | |
| SCHEMBL4890013 | 0.87 | MAPT (0.57) | MAPTALDH1A1CYP1A2CYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | MAPT 4603/4885ALDH1A1 464/4885OGG1 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.