SCHEMBL4886536

SCHEMBL4886536

CCOc1ccc(Cl)c(B(c2c(Cl)ccc(OCC)c2Cl)c2c(Cl)ccc(OCC)c2Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
RORC P51449 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.38
TSHR P16473 4/20 0.37
LARS1 Q9P2J5 2/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 3/20 0.35
LMNA P02545 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HTT P42858 1/20 0.35
ERN1 O75460 1/20 0.34
GAA P10253 2/20 0.33
XBP1 P17861 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12300309 0.79 L3MBTL1 (0.42) MAPTL3MBTL1RORCRAB9AATM
SCHEMBL4881673 0.78 ALDH1A1 (0.38) MAPTL3MBTL1RAB9AHPGDALDH1A1
SCHEMBL4889741 0.77 LMNA (0.36) MAPTL3MBTL1RORCRAB9AATM
SCHEMBL29954273 0.72 TSHR (0.39) L3MBTL1RORCATMTSHRHPGD
SCHEMBL16668301 0.72 TSHR (0.39) L3MBTL1RORCATMTSHRHPGD
SCHEMBL21192744 0.71 ERN1 (0.43) MAPTL3MBTL1RORCRAB9AATM
SCHEMBL3785688 0.70 ALDH1A1 (0.52) MAPTL3MBTL1RAB9AATMALDH1A1
SCHEMBL1547751 0.69 L3MBTL1 (0.54) MAPTL3MBTL1RAB9AATMTSHR
SCHEMBL19155762 0.69 MAPT (0.41) MAPTL3MBTL1RORCRAB9AATM
SCHEMBL18052935 0.69 MAPT (0.41) MAPTL3MBTL1RORCRAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817318-B1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS NIPPON CATALYTIC CHEM IND (JP) 2013-08-28 EP disclosed
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds NIPPON SHOKUBAI CO., LTD. (JP) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds AR, AHR, BCL6 MAPT 1790/4885L3MBTL1 2660/4885RORC 959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.