SCHEMBL4887282

SCHEMBL4887282

CC[CH]Oc1cccc(OC)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
KDM4E B2RXH2 4/20 0.53
LMNA P02545 2/20 0.53
TP53 P04637 2/20 0.53
MAPK1 P28482 2/20 0.53
ALDH1A1 P00352 2/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TLR2 O60603 1/20 0.49
ERN1 O75460 1/20 0.49
TLR1 Q15399 1/20 0.49
TLR6 Q9Y2C9 1/20 0.49
CA12 O43570 1/20 0.47
ALOX5 P09917 1/20 0.47
PTGS2 P35354 1/20 0.47
IDO1 P14902 1/20 0.45
NPC1 O15118 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Syringol SCHEMBL20564590 0.82 KDM4E (0.70) MAPTKDM4ELMNATP53MAPK1
SCHEMBL8747611 0.81 ALDH1A1 (0.46) MAPTKDM4ELMNATP53MAPK1
SCHEMBL5778963 0.80 CA1 (0.56) LMNATP53MAPK1ALDH1A1CA12
Syringol SCHEMBL156388 0.79 KDM4E (0.80) MAPTKDM4ELMNATP53MAPK1
SCHEMBL1264521 0.77 CA2 (0.52) MAPTKDM4ELMNATP53MAPK1
Syringol SCHEMBL7610366 0.77 KDM4E (0.76) MAPTKDM4ELMNATP53MAPK1
Syringol SCHEMBL8986496 0.77 KDM4E (0.76) MAPTKDM4ELMNATP53MAPK1
Syringol SCHEMBL6049240 0.77 KDM4E (0.76) MAPTKDM4ELMNATP53MAPK1
SCHEMBL21383074 0.76 HNF4A (0.41) MAPTKDM4ELMNATP53MAPK1
SCHEMBL1702501 0.75 CA2 (0.50) MAPTKDM4ELMNATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof MICRO SCIENCE TECH CO., LTD. (KR) 2008-08-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof PCNA, HSF1, TERB1 MAPT 1154/4885KDM4E 1725/4885LMNA 2084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.