SCHEMBL4887318

SCHEMBL4887318

c1cc[n+](-c2cccc3ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
HSD17B10 Q99714 5/20 0.42
CYP2A6 P11509 3/20 0.42
TSHR P16473 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP1A2 P05177 4/20 0.39
HPGD P15428 3/20 0.39
CYP3A4 P08684 2/20 0.39
KEAP1 Q14145 1/20 0.39
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
HPRT1 P00492 1/20 0.39
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38
CDC25B P30305 1/20 0.38
ATM Q13315 1/20 0.38
CHAT P28329 1/20 0.36
HIF1A Q16665 1/20 0.36
CYP1B1 Q16678 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18925756 0.85 DRD4 (0.36) ALDH1A1DRD4DRD3
SCHEMBL12715301 0.84 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL15210855 0.81 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRTDP1CYP1A2
Hydrochloric Acid SCHEMBL1246276 0.79 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP1A2HPGDHIF1A
Bromide SCHEMBL8665049 0.78 ALDH1A1 (0.37) ALDH1A1HSD17B10TDP1CYP1A2HPGD
SCHEMBL16469714 0.77 ACHE (0.46) ALDH1A1ATMACHE
SCHEMBL28508090 0.77 ALDH1A1 (0.34) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL2913990 0.77 ALDH1A1 (0.53) ALDH1A1HSD17B10TDP1HPGDACHE
SCHEMBL16470407 0.75 CYP1A2 (0.39) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL4341300 0.74 DRD4 (0.51) ALDH1A1HPGDDRD4DRD3ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249239-B1 Process for the formation of direct positive images FUJI PHOTO FILM CO LTD (JP) 1995-01-25 EP claimed
EP-0318987-B1 DIRECT POSITIVE PHOTOGRAPHIC LIGHTSENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-02-03 EP claimed
EP-0276842-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1992-07-29 EP claimed
EP-0318988-B1 DIRECT POSITIVE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1992-07-15 EP claimed
US-5015561-A Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US claimed
US-4981780-A High maximum density and low minimum density as well as realizing high fradient at a highlight portion by using a nucleation compound and metallized silver halide FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US claimed
US-4968596-A DEVELOPMENT IN PRESENCE OF NUCLEATION AGENT FUJI PHOTO FILM CO. LTD. (JP) 1990-11-06 US claimed
US-4966836-A QUATERNARY HETEROCYCLIC NUCLEATING AGENT WITH HETEROCYCLIC ACCELERATOR, GOOD DENSITIES FUJI PHOTO FILM CO., LTD. (JP) 1990-10-30 US claimed
US-4954427-A Development of light-sensitive material in the presence of a nucleating agent and a nuceation accelerator FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US claimed
US-4877723-A EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US claimed
US-4859579-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US claimed
EP-0318987-A1 Direct positive photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-07 EP claimed
EP-0318988-A1 Direct positive photographic light sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-07 EP claimed
EP-0315890-A1 Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1989-05-17 EP claimed
EP-0276842-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-08-03 EP claimed
EP-0249239-A2 Process for the formation of direct positive images FUJI PHOTO FILM CO., LTD. (JP) 1987-12-16 EP claimed
US-11892401-B2 Boronic acid appended naphthyl-pyridinium fluorescent saccharide sensors for early detection of gastrointestinal diseases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-02-06 US disclosed
US-20210364437-A1 BORONIC ACID APPENDED NAPHTHYL-PYRIDINIUM FLUORESCENT SACCHARIDE SENSORS FOR EARLY DETECTION OF GASTROINTESTINAL DISEASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2021-11-25 US disclosed
EP-0267482-A2 Direct positive color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-05-18 EP disclosed
EP-0249239-A2 Process for the formation of direct positive images FUJI PHOTO FILM CO., LTD. (JP) 1987-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11892401-B2 Boronic acid appended naphthyl-pyridinium fluorescent saccharide sensors for early detection of gastrointestinal diseases SI, FABP2, FABP6 ALDH1A1 1758/4885HSD17B10 2158/4885CYP2A6 682/4885
US-20210364437-A1 BORONIC ACID APPENDED NAPHTHYL-PYRIDINIUM FLUORESCENT SACCHARIDE SENSORS FOR EARLY DETECTION OF GASTROINTESTINAL DISEASES SI, FABP2, FABP6 ALDH1A1 1758/4885HSD17B10 2158/4885CYP2A6 682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.