Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 14/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4890482 | 0.83 | CYP2C9 (0.58) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4888747 | 0.78 | CYP2C9 (0.47) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14021423 | 0.72 | CYP3A4 (0.81) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4880985 | 0.72 | CYP3A4 (1.00) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4879933 | 0.72 | PRNP (0.33) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14021422 | 0.71 | CYP3A4 (1.00) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL4888780 | 0.71 | CYP3A4 (0.98) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14021425 | 0.71 | CYP3A4 (0.83) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL4881839 | 0.71 | CYP3A4 (0.98) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14021419 | 0.71 | CYP3A4 (0.55) | CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | ALPI, PYGL, PPIP5K2 | CYP2C9 1357/4885CYP3A4 215/4885CYP1A2 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.