Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 2/20 | 0.31 |
| ▸ | ATP4B | P51164 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575125 | 0.81 | APP (0.34) | HTTL3MBTL1LMNAHPGDRXFP1 | |
| SCHEMBL25103350 | 0.81 | NMT1 (0.33) | PRNPHTTL3MBTL1RXFP1GAA | |
| SCHEMBL31211004 | 0.79 | AKT1 (0.40) | PRNPNPSR1RXFP1GAAALDH1A1 | |
| SCHEMBL16268761 | 0.72 | MEN1 (0.36) | L3MBTL1LMNARXFP1MAPT | |
| SCHEMBL4888747 | 0.72 | CYP2C9 (0.47) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL4887393 | 0.72 | CYP2C9 (0.56) | ALDH1A1CYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL25974150 | 0.72 | KMT2A (0.39) | NPSR1HTTHPGDTSHRGAA | |
| SCHEMBL10921260 | 0.71 | ATP4A (0.53) | ALDH1A1MAPTATP4AATP4BCYP3A4 | |
| SCHEMBL4890938 | 0.70 | CYP3A4 (0.61) | ATP4AATP4BCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL5212872 | 0.69 | ATP4A (0.52) | HTTL3MBTL1ALDH1A1MAPTATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311740-A1 | IMIDAZOPYRIDINE DERIVATIVES AS ACID PUMP ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-12-09 | — | — | US | disclosed |
| US-20100311740-A1 | IMIDAZOPYRIDINE DERIVATIVES AS ACID PUMP ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-12-09 | — | — | US | disclosed |
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
| WO-2007003386-A9 | IMIDAZOPYRIDINE DERIVATIVES AS ACID PUMP ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-09-18 | — | — | WO | disclosed |
| US-7223771-B2 | Tricyclic imidazopyridines | ALTANA PHARMA AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-7223771-B2 | Tricyclic imidazopyridines | ALTANA PHARMA AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-7223771-B2 | Tricyclic imidazopyridines | ALTANA PHARMA AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-7189736-B2 | Prodrugs of imidazopyridine derivatives | ALTANA PHARMA AG (DE) | 2007-03-13 | — | — | US | disclosed |
| EP-1313739-A1 | ALKYLATED IMIDAZOPYRIDINE DERIVATIVES | ALTANA Pharma AG (DE) | 2003-05-28 | — | — | EP | disclosed |
| EP-1303519-A1 | TRICYCLIC IMIDAZOPYRIDINES | ALTANA Pharma AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001072748-A9 | IMIDAZOPYRIDIN-8-ONES | ALTANA PHARMA AG (DE) | 2003-04-10 | — | — | WO | disclosed |
| EP-1286993-A1 | IMIDAZOPYRIDIN-8-ONES | ALTANA Pharma AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2003014123-A1 | TRICYCLIC IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2003-02-20 | — | — | WO | disclosed |
| WO-2002034749-A1 | POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS | ALTANA PHARMA AG (DE) | 2002-05-02 | — | — | WO | disclosed |
| WO-2001072757-A1 | TRICYCLIC IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072748-A1 | IMIDAZOPYRIDIN-8-ONES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072754-A1 | ALKYLATED IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072756-A1 | PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | ALPI, PYGL, PPIP5K2 | PRNP 1023/4885NPSR1 2158/4885HTT 4293/4885 |
| US-20100311740-A1 | IMIDAZOPYRIDINE DERIVATIVES AS ACID PUMP ANTAGONISTS | HRH2, GIPR, MLNR | PRNP 3637/4885NPSR1 1013/4885HTT 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.