Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | BHMT | Q93088 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851690 | 0.83 | PTGS1 (0.39) | PTGS1SLC7A11NOS3NOS1NOS2 | |
| Serine SCHEMBL418634 | 0.81 | PTGS1 (0.48) | PTGS1SLC7A11SLC1A1ENPEPGRIK1 | |
| Serine SCHEMBL6568300 | 0.80 | SLC1A1 (0.34) | PTGS1SLC7A11NOS3NOS1NOS2 | |
| Serine SCHEMBL4887749 | 0.80 | PTGS1 (0.55) | PTGS1SLC7A11NOS3NOS1NOS2 | |
| Serine SCHEMBL1018118 | 0.78 | PTGS1 (0.48) | PTGS1SLC7A11SLC1A1ENPEPGRIK1 | |
| Serine SCHEMBL4851695 | 0.76 | PTGS1 (0.50) | PTGS1SLC7A11NOS3NOS1NOS2 | |
| SCHEMBL5074148 | 0.74 | PTGS1 (0.56) | PTGS1SLC7A11SLC1A1ENPEPGRIK1 | |
| Serine SCHEMBL27873098 | 0.73 | BHMT (0.45) | PTGS1SLC7A11NOS3NOS1NOS2 | |
| Serine SCHEMBL1514152 | 0.73 | BHMT (0.45) | PTGS1SLC7A11NOS3NOS1NOS2 | |
| SCHEMBL9298602 | 0.73 | PTGS1 (0.36) | PTGS1SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688489-A | Non-receptor mediated imaging agents | RESOLUTION PHARMACEUTICALS, INC. (CA) | 1997-11-18 | — | — | US | claimed |
| US-7320784-B1 | Immobilized labeling compounds and methods | BRACCO IMAGING S.P.A. (IT) | 2008-01-22 | — | — | US | disclosed |
| EP-1154803-B1 | IMMOBILIZED LABELING COMPOUNDS AND METHODS | BRACCO INT BV (NL) | 2004-11-17 | — | — | EP | disclosed |
| EP-1154803-A1 | IMMOBILIZED LABELING COMPOUNDS AND METHODS | Bracco International B.V. (NL) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048639-A1 | IMMOBILIZED LABELING COMPOUNDS AND METHODS | RESOLUTION PHARMACEUTICALS INC. (CA) | 2000-08-24 | — | — | WO | disclosed |