SCHEMBL4888155

SCHEMBL4888155

C=C(C#N)C(=O)OCCCOCC

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.65
TSHR P16473 6/20 0.65
THRB P10828 1/20 0.49
CYP2C9 P11712 1/20 0.33
KMT2A Q03164 2/20 0.33
DNM1 Q05193 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
PKM P14618 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21932802 0.98 TSHR (0.62) ALDH1A1TSHRTHRBCYP2C9KMT2A
SCHEMBL7545698 0.97 ALDH1A1 (0.65) ALDH1A1TSHRTHRBCYP2C9KMT2A
SCHEMBL11285683 0.93 TSHR (0.61) ALDH1A1TSHRTHRBCYP2C9KMT2A
SCHEMBL450203 0.89 TSHR (0.69) ALDH1A1TSHRTHRBCYP2C9KMT2A
SCHEMBL4888255 0.88 TSHR (0.58) ALDH1A1TSHRTHRBLMNAMAPT
SCHEMBL4892572 0.88 TSHR (0.58) ALDH1A1TSHRTHRBDNM1NPSR1
SCHEMBL28722802 0.88 TSHR (0.67) ALDH1A1TSHRTHRBCYP2C9KMT2A
SCHEMBL11279786 0.88 TSHR (0.67) ALDH1A1TSHRTHRBCYP2C9KMT2A
SCHEMBL4578754 0.87 TSHR (0.63) ALDH1A1TSHRTHRBDNM1POLB
Enbucrilate SCHEMBL11173752 0.86 TSHR (0.56) ALDH1A1TSHRTHRBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323137-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO. LTD. (JP) 2023-10-12 US disclosed
US-20230272140-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO., LTD. (JP) 2023-08-31 US disclosed
CN-115803396-A Composition for sealing covered electric wire and covered electric wire 东亚合成株式会社 2023-03-14 CN disclosed
CN-115362230-A Low odor cyanoacrylate compositions 汉高股份有限及两合公司 2022-11-18 CN disclosed
CN-110663091-B Composition for sealing coated electric wire 东亚合成株式会社 2022-03-22 CN disclosed
WO-2022004844-A1 COMPOSITION FOR COVERED-WIRE SEAL, AND COVERED WIRE 東亞合成株式会社 2022-01-06 WO disclosed
CN-113874459-A Flexible photocurable cyanoacrylate compositions 汉高知识产权控股有限责任公司 2021-12-31 CN disclosed
WO-2021060390-A1 COMPOSITION FOR COVERED-WIRE SEAL AND COVERED WIRE 東亞合成株式会社 2021-04-01 WO disclosed
US-20200152350-A1 COMPOSITION FOR SEALING COVERED WIRE TOAGOSEI CO., LTD. (JP) 2020-05-14 US disclosed
CN-110663091-A Composition for sealing coated electric wire 东亚合成株式会社 2020-01-07 CN disclosed
US-20180340130-A1 LUBRICANT COMPOSITION NOK KLUBER., LTD (JP) 2018-11-29 US disclosed
US-9096778-B2 Cyanoacrylate adhesive with improved water resistance Henkel IP & Holding GmbH (DE) 2015-08-04 US disclosed
EP-2511355-B1 Cyanoacrylate adhesive with improved water resistance HENKEL IRELAND LTD (DE) 2013-10-23 EP disclosed
US-20130174981-A1 CYANOACRYLATE ADHESIVE WITH IMPROVED WATER RESISTANCE HENKEL IRELAND LIMITED (DE) 2013-07-11 US disclosed
WO-2012139965-A1 CYANOACRYLATE ADHESIVE WITH IMPROVED WATER RESISTANCE HENKEL IRELAND LTD. (IE) 2012-10-18 WO disclosed
EP-2511355-A1 Cyanoacrylate adhesive with improved water resistance Henkel Ireland Ltd. (IE) 2012-10-17 EP disclosed
US-20080293872-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-27 US disclosed
US-20080287574-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-20 US disclosed