Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545698 | 0.97 | ALDH1A1 (0.65) | TSHRALDH1A1THRBZDHHC20CYP4F2 | |
| SCHEMBL21932802 | 0.95 | TSHR (0.62) | TSHRALDH1A1THRBZDHHC20CYP4F2 | |
| SCHEMBL4888155 | 0.93 | ALDH1A1 (0.65) | TSHRALDH1A1THRBCYP2C9KMT2A | |
| SCHEMBL11279786 | 0.92 | TSHR (0.67) | TSHRALDH1A1THRBEPHX2CYP2C9 | |
| SCHEMBL28722802 | 0.92 | TSHR (0.67) | TSHRALDH1A1THRBEPHX2CYP2C9 | |
| SCHEMBL450203 | 0.90 | TSHR (0.69) | TSHRALDH1A1THRBEPHX2CYP2C9 | |
| SCHEMBL4892534 | 0.89 | TSHR (0.58) | TSHRALDH1A1THRBZDHHC20KMT2A | |
| SCHEMBL11266934 | 0.87 | TSHR (0.56) | TSHRALDH1A1THRBEPHX2ZDHHC20 | |
| SCHEMBL16174654 | 0.86 | TSHR (0.54) | TSHRALDH1A1THRBEPHX2ZDHHC20 | |
| SCHEMBL21932828 | 0.86 | TSHR (0.54) | TSHRALDH1A1THRBEPHX2ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364876-A | QUICK-SETTING ADHESIVES, COATINGS, MOLDING MATERIALS | TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-12-21 | — | — | US | disclosed |