SCHEMBL450203

SCHEMBL450203

C=C(C#N)C(=O)OCCOCC

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.69
ALDH1A1 P00352 5/20 0.69
THRB P10828 2/20 0.61
CYP2C9 P11712 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31
EPHX2 P34913 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11279786 0.98 TSHR (0.67) TSHRALDH1A1THRBCYP2C9MEN1
SCHEMBL28722802 0.98 TSHR (0.67) TSHRALDH1A1THRBCYP2C9MEN1
SCHEMBL11285683 0.90 TSHR (0.61) TSHRALDH1A1THRBCYP2C9MEN1
SCHEMBL4888155 0.89 ALDH1A1 (0.65) TSHRALDH1A1THRBCYP2C9MEN1
SCHEMBL7545698 0.89 ALDH1A1 (0.65) TSHRALDH1A1THRBCYP2C9MEN1
SCHEMBL16290353 0.88 TSHR (0.61) TSHRALDH1A1THRBTP53HIF1A
SCHEMBL3786036 0.88 TSHR (0.61) TSHRALDH1A1THRBTP53HIF1A
SCHEMBL3791084 0.88 TSHR (0.61) TSHRALDH1A1THRBTP53HIF1A
SCHEMBL21932802 0.88 TSHR (0.62) TSHRALDH1A1THRBCYP2C9MEN1
SCHEMBL605391 0.87 TSHR (0.61) TSHRALDH1A1THRBCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 987 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717744-A1 USE OF A COMPOSITION BASED ON CYANOACRYLATE AND (METH)ACRYLATE Bostik SA (FR) 2026-04-01 EP claimed
US-20260041183-A1 ADHESIVE FOR COSMETIC ARTICLE AND METHOD OF FORMING FULLER H B CO (US) 2026-02-12 US claimed
US-20250215132-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2025-07-03 US claimed
WO-2025119862-A1 COMPOSITION COMPRISING N-HEPTYLCYANOACRYLATE BOSTIK SA (FR) 2025-06-12 WO claimed
EP-4567084-A1 COMPOSITION COMPRISING N-HEPTYLCYANOACRYLATE Bostik SA (FR) 2025-06-11 EP claimed
CN-116209729-B Thickener for cyanoacrylate-based adhesives 旭化成株式会社 2025-04-08 CN claimed
EP-4504844-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2025-02-12 EP claimed
US-12209158-B2 (Meth)acrylic composition comprising a modified polyurethane BOSTIK SA (FR) 2025-01-28 US claimed
US-12157784-B2 Two-part curable composition BOSTIK SA (FR) 2024-12-03 US claimed
CN-114621398-B Stretchable cyanoacrylate tissue adhesives and uses thereof 香港科技大学 2024-04-30 CN claimed
EP-0460806-A2 Electrophotographic sensitive member Kinoshita, Koichi (JP) 1991-12-11 EP claimed
US-4981483-A CYANOACRYLATE-ACRYLIC ACID COPOLYMER MOSKOVSKY NAUCHNO-ISSLEDOVATELSKY ONKOLOGICHESKY INSTITUT IMENI P.A. GERTSENA (RU) 1991-01-01 US claimed
US-4933220-A Using cyanoacrylate ARMSTRONG WORLD INDUSTRIES, INC. (US) 1990-06-12 US claimed
EP-0323720-A1 Adhesive UHU GmbH (DE) 1989-07-12 EP claimed
EP-0163757-A1 Adhesive composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-11 EP claimed
US-4496685-A COMPRISING ALPHA CYANOACRYLATE MONOMER AND A PHOSPHAZENE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-01-29 US claimed
US-4393183-A STORAGE STABILITY, BONDING STRENGTH TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1983-07-12 US claimed
US-4321180-A COMPRISING AN ALKYLOXYALKYL 2-CYANOACRYLATE, MOISTURE AND A POLYMERIZATION INHIBITOR TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1982-03-23 US claimed
US-4313865-A A Z-CYANOACRYLATE AND A 1,1-OISUBSTITUTED DIENE PROVIDES FLEXIBILITY, HEAT RESISTANCE, IMPACT RESISTANCE, PEEL RESISTANCE AND WATER RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-02-02 US claimed
EP-0026665-A1 Quick-setting adhesive composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041183-A1 ADHESIVE FOR COSMETIC ARTICLE AND METHOD OF FORMING KRT18, CDH1, CFL1 TSHR 3226/4885ALDH1A1 556/4885THRB 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.