SCHEMBL488858

SCHEMBL488858

OB(O)c1ccc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL15577214 0.87 DAO (0.30)
Anthracene SCHEMBL29286582 0.87 CA1 (0.42)
SCHEMBL28813207 0.77 DAO (0.35)
SCHEMBL8966590 0.67 MAOA (0.32)
SCHEMBL321446 0.65 DAO (0.52)
SCHEMBL6556685 0.64 HDAC8 (0.31)
SCHEMBL8168359 0.62
SCHEMBL5148010 0.61
SCHEMBL243709 0.61
SCHEMBL2965760 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343091-A Simple production method of pyrrole-2-boric acid pinacol ester 陕西科技大学 2024-01-05 CN claimed
US-7317037-B2 Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof WYETH (US) 2008-01-08 US claimed
EP-1776107-A1 PROGESTERONE RECEPTOR MODULATORS COMPRISING PYRROLE-OXINDOLE DERIVATIVES AND USES THEREOF Wyeth (US) 2007-04-25 EP claimed
WO-2006023109-A1 PROGESTERONE RECEPTOR MODULATORS COMPRISING PYRROLE-OXINDOLE DERIVATIVES AND USES THEREOF WYETH (US) 2006-03-02 WO claimed
US-20060030717-A1 Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof WYETH (US) 2006-02-09 US claimed
CN-122094950-A Ligand compound with quinoline structure, and radioactive or non-radioactive marker and application thereof 2026-05-26 CN disclosed
WO-2026104681-A1 NEW SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed
WO-2026102212-A1 MACROCYCLIC MCL-1 INHIBITORS VANDERBILT UNIVERSITY (US) 2026-05-15 WO disclosed
EP-4212523-B1 PYRAZOLE AMIDE COMPOUNDS AS IRAK INHIBITORS RIGEL PHARMACEUTICALS INC (US) 2026-05-06 EP disclosed
WO-2025087466-A2 LIGAND COMPOUND OF QUINOLINE STRUCTURE, AND RADIOACTIVE OR NON-RADIOACTIVE MARKER THEREOF AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-05-01 WO disclosed
WO-2025087229-A1 LIGAND COMPOUND OF QUINOLINE STRUCTURE, RADIOACTIVE OR NON-RADIOACTIVE MARKER, AND USE 四川科伦博泰生物医药股份有限公司 2025-05-01 WO disclosed
WO-2025082283-A1 LIGAND COMPOUND OF CYCLOPEPTIDE STRUCTURE, NUCLIDE MARKER THEREOF, PHARMACEUTICAL COMPOSITION, AND USE 四川科伦博泰生物医药股份有限公司 2025-04-24 WO disclosed
EP-0546082-B1 HERBICIDAL PYRROLESULFONYLUREAS DU PONT (US) 1996-12-18 EP disclosed
US-5585328-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-17 US disclosed
WO-1996021456-A1 INHIBITORS OF PRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1996-07-18 WO disclosed
US-5472933-A Plant growth regulators E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-05 US disclosed
EP-0641347-A1 METHOD FOR MAKING A PROLINEBORONATE ESTER BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 1995-03-08 EP disclosed
EP-0546082-A1 HERBICIDAL PYRROLESULFONYLUREAS. DU PONT (US) 1993-06-16 EP disclosed
WO-1993010127-A1 METHOD FOR MAKING A PROLINEBORONATE ESTER BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1993-05-27 WO disclosed
WO-1992004319-A1 HERBICIDAL PYRROLESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-19 WO disclosed