SCHEMBL6556685

SCHEMBL6556685

Fc1c(F)c(F)c(B(c2ccc[nH]2)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28813207 0.78 DAO (0.35) HDAC8HDAC6
SCHEMBL488858 0.64
SCHEMBL5189478 0.63
SCHEMBL56560 0.63
SCHEMBL619771 0.62 TRPV6 (0.38)
SCHEMBL1264372 0.62 TRPV6 (0.38)
SCHEMBL2160899 0.61 CDK2 (0.38) HDAC8HDAC6
Water SCHEMBL1494538 0.61 TRPV6 (0.36)
SCHEMBL5677136 0.60 ALDH1A1 (0.34)
Ammonia Solution, Strong SCHEMBL22116164 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054914-B1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND BASELL POLYOLEFINE GMBH (DE) 2004-03-03 EP disclosed
EP-1054914-A1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND Basell Polyolefine GmbH (DE) 2000-11-29 EP disclosed
WO-2000035973-A1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND WHICH CONTAINS BORON TARGOR GMBH (DE) 2000-06-22 WO disclosed