Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556685 | 0.78 | HDAC8 (0.31) | HDAC8HDAC6 | |
| SCHEMBL488858 | 0.77 | — | — | |
| SCHEMBL8966590 | 0.71 | MAOA (0.32) | — | |
| SCHEMBL5148010 | 0.65 | — | — | |
| SCHEMBL1375840 | 0.65 | — | — | |
| SCHEMBL630634 | 0.62 | HDAC6 (0.41) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL380666 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL7988951 | 0.60 | HDAC6 (0.40) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL30659527 | 0.60 | — | — | |
| SCHEMBL14953931 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923089-B | The synthetic method of a kind of center non-coordination ternary porphyrin compound | JIANGSU UNIVERSITY (CN) | 2015-12-30 | — | — | CN | disclosed |
| CN-103923089-A | Synthesis method for triphyrin compound with no center coordination | UNIV JIANGSU | 2014-07-16 | — | — | CN | disclosed |