Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 15/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893634 | 0.84 | KIF11 (0.42) | KIF11CYP11B1CYP11B2BRD4 | |
| SCHEMBL14154359 | 0.78 | KIF11 (0.47) | KIF11CYP11B1CYP11B2BRD4 | |
| SCHEMBL4596423 | 0.78 | KIF11 (0.47) | KIF11CYP11B1CYP11B2BRD4 | |
| Trifluoroacetic Acid SCHEMBL4595122 | 0.77 | KIF11 (0.42) | KIF11BRD4 | |
| Trifluoroacetic Acid SCHEMBL4596431 | 0.77 | KIF11 (0.42) | KIF11BRD4 | |
| SCHEMBL17324425 | 0.72 | GAA (0.48) | RIPK1 | |
| SCHEMBL18744960 | 0.72 | GAA (0.48) | RIPK1 | |
| SCHEMBL4596430 | 0.71 | KIF11 (0.59) | KIF11CYP11B1CYP11B2 | |
| SCHEMBL4595242 | 0.69 | KIF11 (0.64) | KIF11CYP11B1CYP11B2 | |
| SCHEMBL17332695 | 0.69 | RIPK1 (0.41) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | claimed |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | KIF11 562/4885RIPK1 3894/4885CYP11B1 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.