Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31570069 | 1.00 | MAPT (0.53) | MAPTHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL8369434 | 0.86 | IKBKB (0.50) | MAPTHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL16298594 | 0.83 | GAA (0.41) | MAPTHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL3785609 | 0.83 | HSD17B10 (0.53) | MAPTHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL28992451 | 0.83 | DCLRE1A (0.47) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL30380433 | 0.83 | DCLRE1A (0.47) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL19199865 | 0.82 | HSD17B10 (0.52) | MAPTHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL559918 | 0.82 | ALDH1A1 (0.41) | MAPTHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL27868391 | 0.82 | MAPT (0.52) | MAPTHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL3793580 | 0.82 | HSD17B10 (0.57) | MAPTHSD17B10MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214845-A1 | ANTIBACTERIAL 6'-MODIFIED 4,5-SUBSTITUTED AMINOGLYCOSIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| WO-2007028012-A2 | ANTIBACTERIAL 6'-N-MODIFIED 4,5-SUBSTITUTED AMINOGLYCOSIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214845-A1 | ANTIBACTERIAL 6'-MODIFIED 4,5-SUBSTITUTED AMINOGLYCOSIDE ANALOGS | FUT6, ALG8, NRDC | MAPT 4625/4885HSD17B10 4143/4885MEN1 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.