SCHEMBL30380433

SCHEMBL30380433

CCc1ccc(-c2ccccc2)cc1CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCLRE1A Q6PJP8 1/20 0.47
DCLRE1B Q9H816 1/20 0.47
BCL2 P10415 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
MAPT P10636 3/20 0.45
CYP1A2 P05177 1/20 0.44
HSD17B1 P14061 2/20 0.43
HPGD P15428 2/20 0.42
NOTUM Q6P988 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
BACE1 P56817 1/20 0.42
ALOX5 P09917 1/20 0.41
ALDH1A1 P00352 2/20 0.41
PTGS2 P35354 1/20 0.41
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28992451 1.00 DCLRE1A (0.47) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL10916725 0.88 HSD17B1 (0.45) BCL2HSD17B1
SCHEMBL455218 0.88 DCLRE1A (0.42) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL13699893 0.86 ALDH1A1 (0.41) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL4888958 0.83 MAPT (0.53) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL31570069 0.83 MAPT (0.53) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL9618333 0.83 SMN1; SMN2 (0.47) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL25047111 0.81 DCLRE1A (0.43) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL17859649 0.81 FFAR1 (0.43) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1
SCHEMBL455838 0.81 DCLRE1A (0.43) DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116042475-A Enterobacter huoshanense enzyme preparation, preparation method and application thereof in tobacco shred treatment 河南中烟工业有限责任公司 2023-05-02 CN disclosed