Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976533 | 0.85 | CYP2A6 (0.50) | NQO1CYP2A6CYP1A2TDP1NPC1 | |
| SCHEMBL28542519 | 0.83 | NQO1 (0.48) | NQO1CYP2A6CYP1A2TDP1NPC1 | |
| SCHEMBL28546208 | 0.81 | NQO1 (0.36) | NQO1CYP2A6CYP1A2TDP1MEN1 | |
| SCHEMBL7501835 | 0.80 | NQO1 (0.46) | NQO1CYP2A6CYP1A2TDP1NPC1 | |
| Methyl Alcohol SCHEMBL27872622 | 0.80 | NQO1 (0.46) | NQO1CYP2A6CYP1A2TDP1MEN1 | |
| SCHEMBL687284 | 0.80 | NQO1 (0.46) | NQO1CYP2A6CYP1A2TDP1NPC1 | |
| SCHEMBL4642683 | 0.80 | CYP2A6 (0.50) | NQO1CYP2A6CYP1A2TDP1NPC1 | |
| SCHEMBL29853846 | 0.80 | CYP2A6 (0.50) | NQO1CYP2A6CYP1A2TDP1NPC1 | |
| SCHEMBL2115679 | 0.80 | CYP1A2 (0.50) | NQO1CYP2A6CYP1A2MEN1NPC1 | |
| SCHEMBL28547051 | 0.79 | NQO1 (0.39) | NQO1CYP2A6CYP1A2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105836-B2 | Chemical inhibitors of mismatch repair | MORPHOTEK, INC. (US) | 2012-01-31 | — | — | US | claimed |
| EP-1351565-B1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC (US) | 2011-03-16 | — | — | EP | claimed |
| US-6982169-B2 | Chemical inhibitors of mismatch repair | MORPHOTEK, INC. (US) | 2006-01-03 | — | — | US | claimed |
| EP-1351565-A4 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1417329-A4 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | MORPHOTEK INC (US) | 2005-05-11 | — | — | EP | claimed |
| EP-1417329-A1 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | Morphotek Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| EP-1351565-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | Morphotek Inc. (US) | 2003-10-15 | — | — | EP | claimed |
| US-20030143586-A1 | Genetic hypermutability of plants for gene discovery and diagnosis | MORPHOTEK, INC. | 2003-07-31 | — | — | US | claimed |
| US-20030091997-A1 | Chemical inhibitors of mismatch repair | EISAI, INC. | 2003-05-15 | — | — | US | claimed |
| WO-2003031937-A2 | GENETIC HYPERMUTABILITY OF PLANTS FOR GENE DISCOVERY AND DIAGNOSIS | MORPHOTEK, INC. (US) | 2003-04-17 | — | — | WO | claimed |
| US-20030068808-A1 | Methods for generating antibiotic resistant microbes and novel antibiotics | MORPHOTEK, INC. | 2003-04-10 | — | — | US | claimed |
| WO-2003012130-A1 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | MORPHOTEK INC. (US) | 2003-02-13 | — | — | WO | claimed |
| WO-2002054856-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC. (US) | 2002-07-18 | — | — | WO | claimed |
| US-11434322-B2 | Sulfobetaine group-comprising reactive compound, polymer thereof, and method of producing the polymer | NAGASE CHEMTEX CORPORATION (JP) | 2022-09-06 | — | — | US | disclosed |
| EP-3604275-B1 | SULFOBETAINE-GROUP-CONTAINING REACTIVE COMPOUND, POLYMER THEREOF, AND METHOD FOR PRODUCING POLYMER | NAGASE CHEMTEX CORP (JP) | 2022-02-16 | — | — | EP | disclosed |
| US-20200131300-A1 | SULFOBETAINE GROUP-CONTAINING REACTIVE COMPOUND, POLYMER THEREOF, AND METHOD FOR PRODUCING POLYMER | NAGASE CHEMTEX CORPORATION (JP) | 2020-04-30 | — | — | US | disclosed |
| WO-2003031937-A2 | GENETIC HYPERMUTABILITY OF PLANTS FOR GENE DISCOVERY AND DIAGNOSIS | MORPHOTEK, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| US-20030068808-A1 | Methods for generating antibiotic resistant microbes and novel antibiotics | MORPHOTEK, INC. | 2003-04-10 | — | — | US | disclosed |
| WO-2003012130-A1 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | MORPHOTEK INC. (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002054856-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC. (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131300-A1 | SULFOBETAINE GROUP-CONTAINING REACTIVE COMPOUND, POLYMER THEREOF, AND METHOD FOR PRODUCING POLYMER | CBR3, SCO2, MSRB3 | NQO1 1236/4885CYP2A6 1665/4885CYP1A2 1895/4885 |
| US-11434322-B2 | Sulfobetaine group-comprising reactive compound, polymer thereof, and method of producing the polymer | CBR3, SCO2, MSRB3 | NQO1 1355/4885CYP2A6 1981/4885CYP1A2 2145/4885 |
| US-20030091997-A1 | Chemical inhibitors of mismatch repair | MSH2, MSH6, PMS2 | NQO1 783/4885CYP2A6 2364/4885CYP1A2 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.