SCHEMBL4889710

SCHEMBL4889710

O=[N+]([O-])c1ccc(N2CC=CN(c3ccc(/N=N/c4ccccc4)cc3)N2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MEN1 O00255 8/20 0.41
KMT2A Q03164 8/20 0.41
RAB9A P51151 6/20 0.41
MAPK1 P28482 3/20 0.41
ALDH1A1 P00352 3/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
NPC1 O15118 4/20 0.40
TNNI3 P19429 1/20 0.40
TNNT2 P45379 1/20 0.40
TNNC1 P63316 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
HSP90AA1 P07900 2/20 0.38
AGTR1 P30556 1/20 0.38
PTPN2 P17706 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8758949 1.00 MAPT (0.41) MAPTSMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL4889720 1.00 MAPT (0.41) MAPTSMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL8758940 1.00 MAPT (0.41) MAPTSMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL2544301 0.87 SIRT6 (0.44) MAPTMEN1KMT2AALDH1A1SCN2A
SCHEMBL3192879 0.74 CFTR (0.39) ADRB1GAA
SCHEMBL29588234 0.74 MEN1 (0.66) MAPTSMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL270426 0.74 MEN1 (0.66) MAPTSMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL270425 0.74 MEN1 (0.66) MAPTSMN1; SMN2MEN1KMT2ARAB9A
Hydrochloric Acid SCHEMBL28545676 0.72 MEN1 (0.64) MAPTSMN1; SMN2MEN1KMT2ARAB9A
Methane SCHEMBL5133892 0.72 ALDH1A1 (0.64) MAPTSMN1; SMN2MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE40218-E1 Electro-chemical deposition system and method of electroplating on substrates LANDAU UZIEL 2008-04-08 US disclosed
EP-0991795-B1 ELECTRO-CHEMICAL DEPOSITION SYSTEM AND METHOD OF ELECTROPLATING ON SUBSTRATES APPLIED MATERIALS INC (US) 2006-02-22 EP disclosed
US-6261433-B1 CELL COMPRISING SUBSTRATE HOLDER, CATHODE ELECTRICALLY CONTACTING SUBSTRATE PLATING SURFACE, ELECTROLYTE CONTAINER HAVING ELECTROLYTE INLET AND OUTLET AND OPENING ADAPTED TO RECEIVE SUBSTRATE, ANODE ELECTRICALLY CONNECTED TO ELECTROLYTE APPLIED MATERIALS, INC. 2001-07-17 US disclosed