SCHEMBL3192879

SCHEMBL3192879

C1=CN(c2ccccc2)NN(c2ccccc2)C1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.39
G6PD P11413 2/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 5/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
USP2 O75604 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11420099 0.89 CYP1A2 (0.35) CFTRG6PDGAAL3MBTL1ALOX15
SCHEMBL9154795 0.78 G6PD (0.41) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL4889710 0.74 MAPT (0.41) GAAADRB1
SCHEMBL8758940 0.74 MAPT (0.41) GAAADRB1
SCHEMBL1230085 0.73 CFTR (0.59) CFTRGAAL3MBTL1HTR3EHTR3B
SCHEMBL9728348 0.69 SMN1; SMN2 (0.37) CFTR
SCHEMBL16361382 0.68 SIGMAR1 (0.40) CFTRG6PDGAAALOX5ALOX15
SCHEMBL44774 0.68 ALOX5 (0.39) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL9728500 0.68 ADRA2A (0.46) CFTR
SCHEMBL9728417 0.67 L3MBTL1 (0.43) GAAL3MBTL1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8455598-B2 Production of elastomeric functionalized olefin polymers EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-06-04 US claimed
US-20120322948-A1 PRODUCTION OF ELASTOMERIC FUNCTIONALIZED OLEFIN POLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-12-20 US claimed
US-20100317463-A1 GOLF BALLS HAVING LAYERS MADE FROM FUNCTIONALIZED ETHYLENE COPOLYMERS ACUSHNET COMPANY 2010-12-16 US claimed
US-7504465-B2 Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-03-17 US claimed
US-20090062475-A1 Production of elastomeric functionalized olefin polymers EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2009-03-05 US claimed
US-20080312393-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof BAUGH LISA S 2008-12-18 US claimed
EP-1704172-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF ExxonMobil Research and Engineering Company (US) 2006-09-27 EP claimed
WO-2005063834-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-07-14 WO claimed
US-20050137369-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2005-06-23 US claimed
US-4322260-A Process for the continuous extrusion forming of a plastic double-walled foam-core conduit MONSANTO COMPANY (US) 1982-03-30 US claimed
US-4279815-A DIAZOTIZATION, COUPLING HERKES FRANK E 1981-07-21 US claimed
EP-4559993-A1 PRODUCTION OF RUBBER COMPOSITIONS FROM END OF LIFE TIRES The Goodyear Tire & Rubber Company (US) 2025-05-28 EP disclosed
US-20250163236-A1 PRODUCTION OF RUBBER COMPOSITIONS FROM END OF LIFE TIRES THE GOODYEAR TIRE & RUBBER COMPANY 2025-05-22 US disclosed
WO-2025023320-A1 GASKET MEMBER 大日本印刷株式会社 2025-01-30 WO disclosed
US-20240124683-A1 RUBBER - FORMING ADDITIVES FROM BIOMASS THROUGH SYNGAS PRODUCTION THE GOODYEAR TIRE & RUBBER COMPANY 2024-04-18 US disclosed
US-4279815-A DIAZOTIZATION, COUPLING HERKES FRANK E 1981-07-21 US disclosed
US-4232106-A Photosensitive compositions containing 2-halomethyl-5-vinyl-1,3,4-oxadiazoles as free radical progenitors FUJI PHOTO FILM CO., LTD. (JP) 1980-11-04 US disclosed
US-3966595-A REVERSE OSMOSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-29 US disclosed
US-3950198-A FUSION OF VINYL PLASTISOL TO HEAT-SENSITIVE BACKING MONSANTO COMPANY (US) 1976-04-13 US disclosed
US-3932296-A AMMONIA DERIVATIVE, QUARTERNARY AMMONIUM COMPOUND THE DOW CHEMICAL COMPANY (US) 1976-01-13 US disclosed