Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL25246498 | 0.98 | CA2 (0.38) | CA2CA1ALDH1A1MAPK1 | |
| SCHEMBL5881249 | 0.88 | CA2 (0.37) | CA2CA1ALDH1A1 | |
| SCHEMBL31222712 | 0.85 | LMNA (0.43) | CA2CA1 | |
| SCHEMBL31222702 | 0.85 | LMNA (0.43) | CA2CA1 | |
| SCHEMBL576011 | 0.82 | CA2 (0.36) | CA2CA1 | |
| SCHEMBL19101965 | 0.82 | CA2 (0.36) | CA2CA1 | |
| SCHEMBL24362707 | 0.80 | CA2 (0.40) | CA2CA1 | |
| SCHEMBL1032931 | 0.78 | CA2 (0.47) | CA2CA1 | |
| SCHEMBL28304895 | 0.78 | CA2 (0.36) | CA2CA1 | |
| SCHEMBL780303 | 0.77 | CA2 (0.35) | CA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| EP-4215525-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-116348109-A | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-106008282-B | The synthetic method of trifluoromethane sulfonic acid ester | 中国科学院上海有机化学研究所 | 2018-01-23 | — | — | CN | disclosed |
| CN-106008282-A | Method for synthesizing trifluoromethanesulfonate | 中国科学院上海有机化学研究所 | 2016-10-12 | — | — | CN | disclosed |
| US-20080227774-A1 | 5,5-DISUBSTITUTED-INDOLIZINONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227774-A1 | 5,5-DISUBSTITUTED-INDOLIZINONE COMPOUNDS | CYP3A5, IPO5, IDO1 | CA2 4683/4885CA1 4842/4885ALDH1A1 372/4885 |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | F7, F11, HABP2 | CA2 2222/4885CA1 2437/4885ALDH1A1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.