Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.73 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.73 |
| ▸ | HTR3B | O95264 | 4/20 | 0.73 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.73 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | HTR5A | P47898 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893397 | 1.00 | HTR3A (0.73) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL4895811 | 1.00 | HTR3A (0.73) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL4893391 | 1.00 | HTR3A (0.73) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL14256388 | 1.00 | HTR3A (0.73) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL4885256 | 1.00 | HTR3A (0.73) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL4895803 | 1.00 | HTR3A (0.73) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL4885263 | 1.00 | HTR3A (0.73) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL4888455 | 0.99 | HTR3A (0.71) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL4888464 | 0.99 | HTR3A (0.71) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL4894688 | 0.99 | HTR3A (0.71) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070944-A1 | Novel methods using aminobenzoic acid compounds | EISAI CO., LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20070015789-A1 | Novel methods using aminobenzoic acid compounds | EISAI CO., LTD. (JP) | 2007-01-18 | — | — | US | disclosed |
| WO-2005007600-A2 | NOVEL METHODS USING AMINOBENZOIC ACID COMPOUNDS | EISAI CO., LTD. (JP) | 2005-01-27 | — | — | WO | disclosed |
| EP-0645391-B1 | Benzamide derivatives | EISAI CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5658925-A | EXHIBITS SEROTONIN ANTAGONISM AND AN ACETYLCHOLINE RELEASE ACCELERATING ACTIVITY | EISAI CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0645391-A2 | Aminobenzoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015789-A1 | Novel methods using aminobenzoic acid compounds | GRIN2B, HTR5A, AADAT | HTR3A 141/4885HTR3E 136/4885HTR3B 110/4885 |
| US-20080070944-A1 | Novel methods using aminobenzoic acid compounds | GRIN2B, HTR5A, AADAT | HTR3A 141/4885HTR3E 136/4885HTR3B 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.