Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 10/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 10/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 9/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498599 | 1.00 | LMNA (0.57) | LMNAHTTPLAAT5PLAAT4PLAAT3 | |
| SCHEMBL4491589 | 0.93 | LMNA (0.49) | LMNAHTTPLAAT5PLAAT4PLAAT3 | |
| SCHEMBL4889438 | 0.93 | LMNA (0.49) | LMNAHTTPLAAT5PLAAT4PLAAT3 | |
| SCHEMBL4488945 | 0.92 | EGFR (0.50) | LMNAHTTPLAAT5PLAAT4PLAAT3 | |
| SCHEMBL4899806 | 0.92 | EGFR (0.50) | LMNAHTTPLAAT5PLAAT4PLAAT3 | |
| SCHEMBL4504410 | 0.87 | RAB9A (0.45) | LMNAHTTPLAAT5PLAAT4PLAAT3 | |
| SCHEMBL4899673 | 0.87 | RAB9A (0.45) | LMNAHTTPLAAT5PLAAT4PLAAT3 | |
| SCHEMBL4503862 | 0.84 | MTNR1A (0.49) | MEN1KMT2A | |
| SCHEMBL4900661 | 0.84 | MTNR1A (0.49) | MEN1KMT2A | |
| SCHEMBL4503995 | 0.82 | APOBEC3A (0.54) | LMNAHTTPLAAT5PLAAT4PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070903-A1 | NEW PYRIMIDINE DERIVATIVES AND NEW PYRIDINE DERIVATIVES | AJINOMOTO CO., INC (JP) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070903-A1 | NEW PYRIMIDINE DERIVATIVES AND NEW PYRIDINE DERIVATIVES | P2RY10, CACNA1B, CACNA1E | LMNA 3830/4885HTT 3802/4885PLAAT5 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.