Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | F2R | P25116 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102161 | 0.91 | F2RL3 (0.67) | F2RL3MAPTMEN1KMT2ALMNA | |
| SCHEMBL11402837 | 0.90 | F2RL3 (0.65) | F2RL3MAPTMEN1KMT2ALMNA | |
| SCHEMBL18092629 | 0.88 | F2RL3 (0.64) | F2RL3MAPTMEN1KMT2ALMNA | |
| SCHEMBL18092648 | 0.87 | F2RL3 (0.65) | F2RL3MAPTMEN1KMT2ALMNA | |
| SCHEMBL4893267 | 0.85 | MAPT (0.69) | F2RL3MAPTMEN1KMT2ALMNA | |
| SCHEMBL18092662 | 0.84 | F2RL3 (0.58) | F2RL3MAPTMEN1KMT2ALMNA | |
| SCHEMBL8687160 | 0.79 | ACLY (0.62) | KMT2AEGFR | |
| SCHEMBL7593404 | 0.77 | KMT2A (0.55) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL18113725 | 0.77 | MEN1 (0.57) | F2RL3MAPTMEN1KMT2ALMNA | |
| SCHEMBL11371463 | 0.77 | F2RL3 (0.61) | F2RL3MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10859585-B2 | Lipid probes and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190293666-A1 | LIPID PROBES AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2019-09-26 | — | — | US | disclosed |
| US-10168342-B2 | Lipid probes and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-01 | — | — | US | disclosed |
| EP-3274712-A1 | LIPID PROBES AND USES THEREOF | The Scripps Research Institute (US) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016160544-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016160544-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20160282369-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2016-09-29 | — | — | US | disclosed |
| US-20160282369-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2016-09-29 | — | — | US | disclosed |
| US-20160282369-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2016-09-29 | — | — | US | disclosed |
| US-20080319046-A1 | SUBSTITUTED SULFONAMIDE-INDOLES | WYETH (US) | 2008-12-25 | — | — | US | disclosed |
| EP-1682530-B1 | PYRROLE SUBSTITUTED INDOLES AS INHIBITORS OF PAI-1 | WYETH CORP (US) | 2007-05-09 | — | — | EP | disclosed |
| CN-1882538-A | Substituted sulfonamide-indole-2-carboxylic acid derivatives as PAI-1 inhibitors | WYETH CORP (US) | 2006-12-20 | — | — | CN | disclosed |
| EP-1682530-A1 | SUBSTITUTED PYRROLE-INDOLES AS INHIBITORS OF PAI-1 | Wyeth (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-1667969-A1 | SUBSTITUTED SULFONAMIDE-INDOLE-2-CARBOXYLIC ACID DERIVATIVES AS PAI-1 INHIBITORS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20050113439-A1 | Substituted pyrrole-indoles | WYETH (US) | 2005-05-26 | — | — | US | disclosed |
| US-20050096377-A1 | Substituted sulfonamide-indoles | WYETH (US) | 2005-05-05 | — | — | US | disclosed |
| WO-2005030756-A1 | SUBSTITUTED PYRROLE-INDOLES AS INHIBITORS OF PAI-1 | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005030715-A1 | SUBSTITUTED SULFONAMIDE-INDOLE-2-CARBOXYLIC ACID DERIVATIVES AS PAI-1 INHIBITORS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | disclosed |
| US-3932482-A | CARDIOTONIC | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319046-A1 | SUBSTITUTED SULFONAMIDE-INDOLES | STS, TPST2, IDO2 | F2RL3 3838/4885MAPT 2124/4885MEN1 3530/4885 |
| US-20050096377-A1 | Substituted sulfonamide-indoles | STS, TPST2, IDO2 | F2RL3 3838/4885MAPT 2124/4885MEN1 3530/4885 |
| US-20050113439-A1 | Substituted pyrrole-indoles | IDO2, IDO1, TPH2 | F2RL3 4047/4885MAPT 935/4885MEN1 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.