Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892981 | 0.80 | KDM4E (0.39) | KDM4EMAPK1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL4895438 | 0.78 | KDM4E (0.41) | KDM4EMAPK1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL4895424 | 0.78 | KDM4E (0.41) | KDM4EMAPK1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL4884281 | 0.76 | KDM4E (0.44) | KDM4EMAPK1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL4896496 | 0.75 | ALDH1A1 (0.44) | KDM4EMAPK1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL4884311 | 0.72 | KDM4E (0.48) | KDM4EL3MBTL1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4893007 | 0.72 | KDM4E (0.41) | KDM4EL3MBTL1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4892012 | 0.72 | KDM4E (0.41) | KDM4EL3MBTL1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4893019 | 0.72 | KDM4E (0.41) | KDM4EL3MBTL1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4884321 | 0.71 | KDM4E (0.47) | KDM4EMAPK1L3MBTL1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | KDM4E 2519/4885MAPK1 3579/4885L3MBTL1 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.