Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635072 | 0.94 | LMNA (0.56) | NAMPTGRIN2BPANK3CCR2FAAH | |
| SCHEMBL4084382 | 0.81 | KMT2A (0.58) | GRIN2BMAPTCA12CA1CA2 | |
| SCHEMBL4897296 | 0.81 | TAS1R3 (0.55) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL6742058 | 0.78 | NAMPT (0.56) | NAMPTGRIN2BPANK3CCR2FAAH | |
| SCHEMBL4635549 | 0.78 | ALDH1A1 (0.64) | EPHX2CA1CA2 | |
| SCHEMBL28363514 | 0.77 | NAMPT (0.66) | NAMPTPANK3CCR2FAAHEPHX2 | |
| SCHEMBL4788456 | 0.77 | NAMPT (0.58) | NAMPTCCR2FAAHLMNAMAPT | |
| SCHEMBL6739530 | 0.77 | NAMPT (0.54) | NAMPTGRIN2BPANK3CCR2FAAH | |
| SCHEMBL14808591 | 0.76 | NAMPT (0.64) | NAMPTPANK3CCR2FAAHEPHX2 | |
| SCHEMBL654242 | 0.75 | POLB (0.65) | NAMPTPANK3CCR2FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300251-A1 | Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300251-A1 | Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors | DPP4, DPP3, DPP8 | NAMPT 3253/4885GRIN2B 1589/4885PANK3 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.