SCHEMBL4892558

SCHEMBL4892558

C=C(C#N)C(=O)OC(CC)OCCC

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4888241 0.91 TSHR (0.45) ALDH1A1TSHR
SCHEMBL4893693 0.89 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL4891423 0.88 ALDH1A1 (0.45) ALDH1A1TSHR
SCHEMBL4888140 0.87 ALDH1A1 (0.55) ALDH1A1TSHR
SCHEMBL4888281 0.82 ALDH1A1 (0.49) ALDH1A1TSHR
SCHEMBL27579595 0.82 ALDH1A1 (0.49) ALDH1A1TSHR
SCHEMBL440641 0.81 ALDH1A1 (0.52) ALDH1A1TSHR
SCHEMBL4892530 0.80 TSHR (0.44) ALDH1A1TSHR
SCHEMBL4885635 0.80 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL4893685 0.80 TSHR (0.38) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN claimed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN claimed
CN-113874459-A Flexible photocurable cyanoacrylate compositions 汉高知识产权控股有限责任公司 2021-12-31 CN disclosed
CN-105246872-B Cyanoacrylate compositions 汉高知识产权控股有限责任公司 2019-08-13 CN disclosed
US-20180340130-A1 LUBRICANT COMPOSITION NOK KLUBER., LTD (JP) 2018-11-29 US disclosed
CN-105246872-A Cyanoacrylate compositions Henkel US IP LLC 2016-01-13 CN disclosed
US-20080293872-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-27 US disclosed
US-20080287574-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-20 US disclosed
US-20060210528-A1 Therapy for tropical diseases ASPIRE BIOTECH, INC. 2006-09-21 US disclosed
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN disclosed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN disclosed
US-20030143189-A1 Therapy for topical diseases ASPIRE BIOTECH, INC. 2003-07-31 US disclosed
WO-2003041686-A2 IMPROVED THERAPY FOR TOPICAL DISEASES MEDLOGIC GLOBAL LIMITED (GB) 2003-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060210528-A1 Therapy for tropical diseases TSLP, TLR3, CUTA ALDH1A1 2037/4885TSHR 3945/4885
US-20030143189-A1 Therapy for topical diseases TSLP, KRT18, CUTA ALDH1A1 1518/4885TSHR 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.