Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130580 | 0.88 | CYP3A4 (0.49) | HDAC1HDAC6CYP3A4PTGS1PTGS2 | |
| SCHEMBL8035118 | 0.85 | CYP3A4 (0.58) | HDAC1HDAC6CYP3A4HTR6 | |
| SCHEMBL8025072 | 0.81 | HDAC1 (0.69) | HDAC1HDAC6HTR6 | |
| Hydrochloric Acid SCHEMBL7131399 | 0.81 | HDAC1 (0.54) | HDAC1HDAC6PTGS1PTGS2SIRT2 | |
| SCHEMBL13141908 | 0.80 | HDAC1 (0.64) | HDAC1HDAC6PTGS1PTGS2 | |
| SCHEMBL10155064 | 0.78 | CYP3A4 (0.51) | HDAC1HDAC6CYP3A4HTR6 | |
| SCHEMBL13142351 | 0.78 | HTR6 (0.69) | CYP3A4PTGS1PTGS2HTR6SIRT2 | |
| SCHEMBL4886182 | 0.77 | PTGS1 (0.54) | CYP3A4PTGS1PTGS2HTR6SIRT2 | |
| SCHEMBL4892347 | 0.76 | PTGS1 (0.46) | CYP3A4PTGS1PTGS2HTR6 | |
| SCHEMBL4127644 | 0.76 | HDAC1 (0.56) | HDAC1HDAC6PTGS1PTGS2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280941-A1 | 8-Phenoxy-Gamma Carboline Derivatives | PHARMA C S.A. (FR) | 2008-11-13 | — | — | US | disclosed |
| EP-1756102-A1 | 8-PHENOXY-GammaCARBOLINE DERIVATIVES | Pharma C S.A. (FR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005095396-A1 | 8-PHENOXY-Ϝ CARBOLINE DERIVATIVES | PHARMA C S.A. (FR) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280941-A1 | 8-Phenoxy-Gamma Carboline Derivatives | CHRNA7, ADRA2C, CHRNE | HDAC1 1187/4885HDAC6 810/4885CYP3A4 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.