Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886182 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2CYP3A4HTR6MCHR1 | |
| SCHEMBL4892790 | 0.76 | HDAC1 (0.50) | PTGS1PTGS2CYP3A4HTR6 | |
| SCHEMBL11217826 | 0.69 | CYP3A4 (0.47) | PTGS1PTGS2CYP3A4HTR6HRH1 | |
| SCHEMBL7130580 | 0.69 | CYP3A4 (0.49) | PTGS1PTGS2CYP3A4HTR6MCHR1 | |
| SCHEMBL13142351 | 0.68 | HTR6 (0.69) | PTGS1PTGS2CYP3A4HTR6HTR2A | |
| SCHEMBL2364891 | 0.68 | SIRT2 (0.41) | HTR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL31078331 | 0.65 | KDM4E (0.47) | PTGS1PTGS2HTR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL31078325 | 0.65 | MAPT (0.49) | PTGS1PTGS2CYP3A4HTR6MCHR1 | |
| Hydrochloric Acid SCHEMBL31078372 | 0.64 | KDM4E (0.46) | PTGS1PTGS2HTR6HTR2AHTR2C | |
| SCHEMBL24417619 | 0.64 | ALDH1A1 (0.47) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280941-A1 | 8-Phenoxy-Gamma Carboline Derivatives | PHARMA C S.A. (FR) | 2008-11-13 | — | — | US | disclosed |
| EP-1756102-A1 | 8-PHENOXY-GammaCARBOLINE DERIVATIVES | Pharma C S.A. (FR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005095396-A1 | 8-PHENOXY-Ϝ CARBOLINE DERIVATIVES | PHARMA C S.A. (FR) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280941-A1 | 8-Phenoxy-Gamma Carboline Derivatives | CHRNA7, ADRA2C, CHRNE | PTGS1 249/4885PTGS2 268/4885CYP3A4 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.