Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896087 | 0.88 | HTT (0.64) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL4887551 | 0.87 | ALDH1A1 (0.43) | ALDH1A1NPSR1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL4889408 | 0.87 | KMT2A (0.45) | ALDH1A1MAPTNPSR1KMT2AKDM4E | |
| SCHEMBL4883870 | 0.87 | ALDH1A1 (0.48) | ALDH1A1NPSR1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL4892539 | 0.86 | GAA (0.43) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL4892536 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HTTKMT2APOLB | |
| SCHEMBL14087769 | 0.83 | ALDH1A1 (0.42) | ALDH1A1NPSR1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL14087797 | 0.83 | HPGD (0.43) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL14102810 | 0.83 | KMT2A (0.45) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL4887003 | 0.82 | HTT (0.57) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | ALDH1A1 276/4885MAPT 3976/4885NPSR1 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.