Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886830 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAMAPK1KMT2A | |
| SCHEMBL4895351 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL4886403 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAMAPK1KMT2A | |
| SCHEMBL19712892 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAMAPK1KMT2A | |
| SCHEMBL23200084 | 0.72 | HPGD (0.58) | ALDH1A1MAPTKMT2AHTTPOLB | |
| SCHEMBL27357988 | 0.72 | PKM (0.52) | ALDH1A1MAPTKMT2APKMHTT | |
| SCHEMBL14281351 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAMAPK1KMT2A | |
| SCHEMBL19726937 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAKMT2APKM | |
| SCHEMBL18415480 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2APKMPOLB | |
| SCHEMBL7976745 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2APKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | L'OREAL (FR) | 2008-01-31 | — | — | US | disclosed |
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | L'OREAL (FR) | 2008-01-31 | — | — | US | disclosed |
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | L'OREAL (FR) | 2008-01-31 | — | — | US | disclosed |
| EP-1853352-A2 | USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF | L'Oréal (FR) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006079568-A2 | USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF | L'OREAL (FR) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | KRT18, TYR, MC1R | ALDH1A1 1607/4885MAPT 1733/4885LMNA 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.