Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4981629 | 0.87 | DRD4 (0.44) | HPGDSMN1; SMN2RAB9AEPHX1MAPT | |
| SCHEMBL23200029 | 0.77 | USP2 (0.51) | HPGDSMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL18415480 | 0.74 | ALDH1A1 (0.51) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5128656 | 0.74 | USP2 (0.61) | HPGDSMN1; SMN2RAB9AEPHX1MAPT | |
| SCHEMBL6409949 | 0.74 | EPHX2 (0.57) | HPGDSMN1; SMN2RAB9AEPHX1MAPT | |
| SCHEMBL15975482 | 0.74 | HPGD (1.00) | HPGDSMN1; SMN2RAB9AEPHX1MAPT | |
| SCHEMBL23200000 | 0.73 | USP2 (0.47) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10061717 | 0.73 | MAPT (0.50) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23200063 | 0.73 | OPRL1 (0.40) | HPGDEPHX1MAPTKMT2AALDH1A1 | |
| SCHEMBL4893134 | 0.72 | ALDH1A1 (0.48) | HPGDMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802503-A1 | UREA DERIVATIVE MODULATORS OF TRYPTOPHAN CATABOLISM | E-Therapeutics plc (GB) | 2021-04-14 | — | — | EP | disclosed |