Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 6/20 | 0.36 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18948660 | 0.83 | RAB9A (0.55) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL19215660 | 0.82 | RAB9A (0.54) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL19737744 | 0.82 | RAB9A (0.54) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL4892941 | 0.81 | FKBP1A (0.49) | HTTTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL4454199 | 0.81 | FKBP1A (0.49) | HTTTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL19737785 | 0.81 | RAB9A (0.52) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL18051442 | 0.80 | RAB9A (0.58) | RAB9AHTTTSHRALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5980951 | 0.79 | FKBP1A (0.48) | TSHRALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL953015 | 0.79 | FKBP1A (0.48) | TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL24131501 | 0.79 | RAB9A (0.50) | RAB9AHTTTSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176923-A1 | Proline Derivatives Used as Pharmaceutical Active Ingredients for the Treatment of Tumors | SALAMA ZOSER B | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176923-A1 | Proline Derivatives Used as Pharmaceutical Active Ingredients for the Treatment of Tumors | PREP, PRAP1, VHL | RAB9A 2917/4885HTT 1976/4885TSHR 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.