Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414796 | 0.69 | — | — | |
| SCHEMBL9604430 | 0.69 | MEN1 (0.32) | ALDH1A1 | |
| SCHEMBL10368806 | 0.69 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL7171007 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNA | |
| Bicarbonate SCHEMBL1081463 | 0.68 | LMNA (0.44) | ALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL11465670 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL11444043 | 0.67 | OPRM1 (0.32) | ALDH1A1 | |
| SCHEMBL8768371 | 0.67 | — | — | |
| SCHEMBL9748596 | 0.67 | — | — | |
| Water SCHEMBL11221025 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399367-B2 | Rust-preventive water-oil separating cleaner composition and a cleaning method using the same | NICCA CHEMICAL CO., LTD. (JP) | 2008-07-15 | — | — | US | disclosed |
| US-20070173425-A1 | Rust-preventive water-oil separating cleaner composition and a cleaning method using the same | NICCA CHEMICAL CO., LTD. (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1683853-A1 | ANTIRUST OIL WATER SEPARATION TYPE DETERGENT COMPOSITION AND METHOD OF CLEANING | Nicca Chemical Co., Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |