Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894236 | 1.00 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL4508092 | 0.84 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL4895770 | 0.83 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL13958636 | 0.83 | P2RX7 (0.58) | P2RX7 | |
| Hydrochloric Acid SCHEMBL4493149 | 0.82 | P2RX7 (0.57) | P2RX7 | |
| Hydrochloric Acid SCHEMBL4511697 | 0.82 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL4508282 | 0.82 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL14113743 | 0.81 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL4892423 | 0.81 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL4898164 | 0.79 | P2RX7 (0.52) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182874-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182874-A1 | Novel Compounds | REN, F12, GPR119 | P2RX7 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.