Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 5/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894649 | 1.00 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4893677 | 0.99 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4893665 | 0.99 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL4885112 | 0.96 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL4885122 | 0.96 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL4888726 | 0.95 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4893581 | 0.95 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4893588 | 0.95 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4895680 | 0.94 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL4893454 | 0.88 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070944-A1 | Novel methods using aminobenzoic acid compounds | EISAI CO., LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20070015789-A1 | Novel methods using aminobenzoic acid compounds | EISAI CO., LTD. (JP) | 2007-01-18 | — | — | US | disclosed |
| EP-0645391-A2 | Aminobenzoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015789-A1 | Novel methods using aminobenzoic acid compounds | GRIN2B, HTR5A, AADAT | ADRA2A 2929/4885ADRA2B 913/4885ADRA2C 3207/4885 |
| US-20080070944-A1 | Novel methods using aminobenzoic acid compounds | GRIN2B, HTR5A, AADAT | ADRA2A 2929/4885ADRA2B 913/4885ADRA2C 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.