Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | WNT3 | P56703 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887310 | 0.88 | ADRA2A (0.37) | RIPK1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL4897407 | 0.84 | CYP1A2 (0.39) | RIPK1KMT2AMEN1 | |
| SCHEMBL4889310 | 0.82 | RIPK1 (0.41) | RIPK1KMT2A | |
| SCHEMBL3774144 | 0.82 | KMT2A (0.34) | RIPK1KMT2A | |
| SCHEMBL8273830 | 0.75 | SCN9A (0.47) | CRHR1RIPK1SCN9ADRD2 | |
| SCHEMBL8274292 | 0.74 | CRHR1 (0.39) | CRHR1WNT3KMT2AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL4894849 | 0.73 | CRHR1 (0.38) | CRHR1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL5310034 | 0.71 | CYP1A2 (0.41) | RIPK1KMT2AMEN1 | |
| SCHEMBL4895917 | 0.71 | GSK3B (0.37) | — | |
| SCHEMBL4897077 | 0.71 | RIPK1 (0.38) | RIPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | DPP4, DPP8, DPP3 | CRHR1 1420/4885RIPK1 3999/4885SCN9A 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.