SCHEMBL4895465

SCHEMBL4895465

O=S(=O)(NCc1ccncc1)c1ccc(I)cc1

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 9/20 0.71
LMNA P02545 9/20 0.71
HTT P42858 8/20 0.71
RAB9A P51151 4/20 0.66
NPC1 O15118 1/20 0.66
ALDH1A1 P00352 2/20 0.62
NR2F2 P24468 2/20 0.62
NAMPT P43490 3/20 0.59
GAA P10253 2/20 0.54
GLA P06280 1/20 0.54
POLB P06746 1/20 0.54
MAPT P10636 1/20 0.54
STAT3 P40763 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
GALR3 O60755 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27083360 0.85 SMN1; SMN2 (0.73) SMN1; SMN2LMNAHTTRAB9ANPC1
SCHEMBL3923271 0.83 SMN1; SMN2 (0.71) SMN1; SMN2LMNAHTTRAB9ANPC1
SCHEMBL7663045 0.83 SMN1; SMN2 (0.71) SMN1; SMN2LMNAHTTRAB9ANPC1
SCHEMBL4662893 0.83 SMN1; SMN2 (1.00) SMN1; SMN2LMNAHTTRAB9ANPC1
SCHEMBL12090287 0.82 NAMPT (0.60) SMN1; SMN2LMNAALDH1A1NAMPT
SCHEMBL3571824 0.81 SMN1; SMN2 (0.68) SMN1; SMN2LMNAHTTRAB9ANPC1
SCHEMBL27083363 0.81 SMN1; SMN2 (0.82) SMN1; SMN2LMNAHTTRAB9ANPC1
SCHEMBL27950177 0.80 CA12 (0.71) SMN1; SMN2LMNAHTTALDH1A1MAPT
SCHEMBL4402015 0.80 SMN1; SMN2 (0.66) SMN1; SMN2LMNAHTTRAB9ANPC1
SCHEMBL5783946 0.80 CYP19A1 (0.79) SMN1; SMN2LMNAHTTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014065411-A1 SULFONAMIDE DERIVATIVE AS HARMFUL-ORGANISM CONTROL AGENT FOR AGRICULTURAL/HORTICULTURAL USE 株式会社エス・ディー・エス バイオテック (JP) 2014-05-01 WO disclosed
EP-1860941-B1 BIPHENYL-N-(4-PYRIDYL) METHYLSUFONAMIDES BASF SE (DE) 2008-11-12 EP disclosed
US-20080161187-A1 Controlling phytopathogenic harmful fungi and harmful arthropodes; combating arthropodal pestsprotecting crops, seeds and non-living materials from infestation by arthropodal pests; insecticides, pesticides, fungicides; miticides; agriculture; veterinary medicine BASF AKTIENGESELLSCHAFT (DE) 2008-07-03 US disclosed
EP-1860941-A1 BIPHENYL-N-(4-PYRIDYL) METHYLSUFONAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-12-05 EP disclosed
WO-2006097489-A1 BIPHENYL-N-(4-PYRIDYL) METHYLSUFONAMIDES BASF AKTIENGESELLSCHAFT (DE) 2006-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161187-A1 Controlling phytopathogenic harmful fungi and harmful arthropodes; combating arthropodal pestsprotecting crops, seeds and non-living materials from infestation by arthropodal pests; insecticides, pesticides, fungicides; miticides; agriculture; veterinary medicine PTPN21, PTPN1, PTPN14 SMN1; SMN2 2697/4885LMNA 4054/4885HTT 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.