Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704149 | 0.91 | CA1 (0.41) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL48955 | 0.91 | ESR1 (0.41) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL12977080 | 0.82 | ESR1 (0.40) | ESR1ESR2CA4POLB | |
| SCHEMBL21439871 | 0.78 | MAOA (0.40) | ESR1ESR2NPC1RAB9ACYP1A2 | |
| SCHEMBL16487200 | 0.77 | NPC1 (0.41) | NPC1RAB9ACYP1A2POLBALDH1A1 | |
| SCHEMBL676007 | 0.77 | CA12 (0.30) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14649181 | 0.76 | ESR1 (0.38) | ESR1ESR2CA4MAPT | |
| SCHEMBL14964364 | 0.75 | ACHE (0.41) | NPC1RAB9APOLBALDH1A1KDM4E | |
| SCHEMBL13043263 | 0.75 | MAPK1 (0.39) | NPC1RAB9ACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL19985748 | 0.74 | LTA4H (0.56) | CA4CA1CA2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852368-B2 | Hard coating composition and resin product with hard coat | NIPPON ARC CO., LTD. (JP) | 2005-02-08 | — | — | US | disclosed |
| US-20030194571-A1 | Hard coating composition and resin product with hard coat | NIPPON ARC CO., LTD. (JP) | 2003-10-16 | — | — | US | disclosed |
| EP-1298177-A1 | HARD COATING COMPOSITION AND RESIN PRODUCT WITH HARD COAT | NIPPON ARC CO., LTD. (JP) | 2003-04-02 | — | — | EP | disclosed |