Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893048 | 0.92 | TSHR (0.42) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL440642 | 0.90 | ATM (0.47) | ALDH1A1TSHRATMHCAR2SMN1; SMN2 | |
| SCHEMBL540751 | 0.86 | ATM (0.47) | ALDH1A1TSHRATMHCAR2SMN1; SMN2 | |
| SCHEMBL487322 | 0.86 | ATM (0.41) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL3786038 | 0.86 | TSHR (0.50) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL3791086 | 0.86 | TSHR (0.50) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL4889702 | 0.85 | ATM (0.56) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL35576 | 0.85 | ATM (0.56) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL4891840 | 0.84 | HCAR2 (0.51) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL3207425 | 0.84 | ATM (0.46) | ALDH1A1TSHRATMHCAR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293872-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20080287574-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-20 | — | — | US | disclosed |