SCHEMBL440642

SCHEMBL440642

COCCCOC(=O)C=CC#N

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
HCAR2 Q8TDS4 4/20 0.42
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TSHR P16473 3/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 4/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
APP P05067 2/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL540751 0.96 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3207425 0.93 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4895739 0.90 ALDH1A1 (0.39) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL487322 0.89 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1602604 0.85 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1527050 0.84 ATM (0.64) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4893048 0.84 TSHR (0.42) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL24797 0.83 ATM (0.70) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4888147 0.82 ATM (0.48) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1452125 0.81 HCAR2 (0.62) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606719-B2 Methods and compositions comprising biodegradable cyanoacrylates FEMASYS INC. (US) 2026-04-21 US claimed
US-20260062590-A1 METHODS AND COMPOSITIONS COMPRISING BIODEGRADABLE CYANOACRYLATES FOR MEDICAL APPLICATIONS FEMASYS INC (US) 2026-03-05 US claimed
EP-4613213-A2 METHODS AND COMPOSITIONS COMPRISING BIODEGRADABLE CYANOACRYLATES FOR MEDICAL APPLICATIONS Femasys, Inc. (US) 2025-09-10 EP claimed
EP-3579890-B1 METHODS AND COMPOSITIONS COMPRISING BIODEGRADABLE CYANOACRYLATES FEMASYS INC (US) 2025-06-18 EP claimed
US-20230390105-A1 METHODS AND DEVICES FOR CONTROLLED DELIVERY POINTILLIST GLOBAL MACRO SERIES OF POINTILLIST PARTNERS LLC 2023-12-07 US claimed
US-20230364304-A1 METHODS OF FORMING BONE INTERFACE SCAFFOLDS Sparta Biopharma LLC (US) 2023-11-16 US claimed
US-11364324-B2 Methods of forming bone interface scaffolds SPARTA BIOPHARMA INC. (US) 2022-06-21 US claimed
US-20220054709-A1 METHODS OF FORMING BONE INTERFACE SCAFFOLDS SPARTA BIOPHARMA INC. 2022-02-24 US claimed
EP-3787533-A1 METHODS AND DEVICES FOR CONTROLLED DELIVERY Femasys, Inc. (US) 2021-03-10 EP claimed
WO-2018148453-A1 METHODS AND COMPOSITIONS COMPRISING BIODEGRADABLE CYANOACRYLATES FEMASYS, INC. (US) 2018-08-16 WO claimed
WO-2006034157-A2 PACKAGE COMPONENTS FOR RADIOCHEMICAL STERILIZATION POLY-MED, INC. (US) 2006-03-30 WO claimed
EP-0952171-B1 Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof POLY MED INC (US) 2006-01-04 EP claimed
US-20050042197-A1 Stabilized polyester/cyanoacrylate tissue adhesive formulation POLY-MED, INC. 2005-02-24 US claimed
US-20040199207-A1 Polyester/cyanoacrylate tissue adhesive compositions POLY-MED, INC. 2004-10-07 US claimed
US-6699940-B2 Cyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom POLY MED, INC. 2004-03-02 US claimed
US-6632450-B1 Adherable biomaterial patches and methods for producing and for using same Gregory, Kenton 2003-10-14 US claimed
US-20030105256-A1 Cyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom POLY-MED, INC. 2003-06-05 US claimed
US-20030069535-A1 Stabilized polyester/cyanoacrylate tissue adhesive formulation POLY-MED, INC. 2003-04-10 US claimed
US-6413539-B1 BLOCK POLYMER POLY-MED, INC. 2002-07-02 US claimed
EP-0952171-A2 Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof Poly-Med Inc. (US) 1999-10-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062590-A1 METHODS AND COMPOSITIONS COMPRISING BIODEGRADABLE CYANOACRYLATES FOR MEDICAL APPLICATIONS PGF, ACR, FGB ATM 446/4885HCAR2 465/4885MAPT 1368/4885
US-12606719-B2 Methods and compositions comprising biodegradable cyanoacrylates MKI67, ACR, PGF ATM 171/4885HCAR2 1197/4885MAPT 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.