SCHEMBL540751

SCHEMBL540751

COCCCCOC(=O)C=CC#N

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
HCAR2 Q8TDS4 4/20 0.44
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HPGD P15428 1/20 0.36
APP P05067 4/20 0.34
KDM4E B2RXH2 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440642 0.96 ATM (0.47) ATMHCAR2ALDH1A1TSHRCYP3A4
SCHEMBL3207425 0.90 ATM (0.46) ATMHCAR2ALDH1A1TSHRMAPT
SCHEMBL487322 0.89 ATM (0.41) ATMHCAR2ALDH1A1TSHRMAPT
SCHEMBL4895739 0.86 ALDH1A1 (0.39) ATMHCAR2ALDH1A1TSHRCYP3A4
SCHEMBL1452125 0.85 HCAR2 (0.62) ATMHCAR2TSHRMAPTRAB9A
SCHEMBL5831233 0.84 ATM (0.64) ATMHCAR2ALDH1A1TSHRCYP3A4
SCHEMBL4893048 0.84 TSHR (0.42) ATMHCAR2ALDH1A1TSHRCYP3A4
SCHEMBL8380051 0.84 HCAR2 (0.64) ATMHCAR2TSHRMAPTRAB9A
SCHEMBL29341 0.84 HCAR2 (0.64) ATMHCAR2TSHRMAPTRAB9A
SCHEMBL2903635 0.84 HCAR2 (0.64) ATMHCAR2TSHRMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3579890-B1 METHODS AND COMPOSITIONS COMPRISING BIODEGRADABLE CYANOACRYLATES FEMASYS INC (US) 2025-06-18 EP claimed
US-20230390105-A1 METHODS AND DEVICES FOR CONTROLLED DELIVERY POINTILLIST GLOBAL MACRO SERIES OF POINTILLIST PARTNERS LLC 2023-12-07 US claimed
EP-3787533-A1 METHODS AND DEVICES FOR CONTROLLED DELIVERY Femasys, Inc. (US) 2021-03-10 EP claimed
US-10471174-B2 Cyanoacrylate medical adhesive and preparation method and use thereof Shen, Wei (CN) 2019-11-12 US claimed
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP claimed
EP-3513744-A1 MESH DISPENSER Ethicon, Inc. (US) 2019-07-24 EP claimed
US-20190175782-A1 NOVEL CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN, WEI (CN) 2019-06-13 US claimed
WO-2018148453-A1 METHODS AND COMPOSITIONS COMPRISING BIODEGRADABLE CYANOACRYLATES FEMASYS, INC. (US) 2018-08-16 WO claimed
EP-3335738-A1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Shen, Wei (CN) 2018-06-20 EP claimed
EP-2740497-B1 Medical adhesive compound AESCULAP AG (DE) 2017-12-06 EP claimed
WO-2008154375-A1 MESH DISPENSER CLOSURE MEDICAL CORPORATION (US) 2008-12-18 WO claimed
US-20080302487-A1 MESH DISPENSER CLOSURE MEDICAL CORPORATION (US) 2008-12-11 US claimed
US-20080241249-A1 Cyanoacrylate composite CLOSURE MEDICAL CORPORATION (US) 2008-10-02 US claimed
EP-1928920-A2 IMPROVED STABILIZER CYANOACRYLATE FORMULATIONS Closure Medical Corporation (US) 2008-06-11 EP claimed
WO-2007041143-A2 IMPROVED STABILIZER CYANOACRYLATE FORMULATIONS CLOSURE MEDICAL CORPORATION (US) 2007-04-12 WO claimed
US-20070078207-A1 Stabilizer cyanoacrylate formulations ETHICON, INC. 2007-04-05 US claimed
EP-1317294-B1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORP (US) 2005-03-16 EP claimed
EP-1317294-A1 ABSORBABLE ADHESIVE COMPOSITIONS Closure Medical Corporation (US) 2003-06-11 EP claimed
US-20020037310-A1 Absorbable adhesive compositions CLOSURE MEDICAL CORPORATION (US) 2002-03-28 US claimed
WO-2002009785-A1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2002-02-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080241249-A1 Cyanoacrylate composite ALOX5, SCD, SCD5 ATM 3776/4885HCAR2 244/4885ALDH1A1 806/4885
US-20020037310-A1 Absorbable adhesive compositions EPCAM, CDH1, ICAM1 ATM 1500/4885HCAR2 120/4885ALDH1A1 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.