Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896385 | 0.79 | POLB (0.31) | ALDH1A1GAAHPGD | |
| SCHEMBL4896400 | 0.79 | POLB (0.31) | ALDH1A1GAAHPGD | |
| SCHEMBL4888010 | 0.72 | F2 (0.36) | ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL4896372 | 0.67 | HDAC6 (0.36) | — | |
| SCHEMBL25316083 | 0.61 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EGAA | |
| SCHEMBL3342250 | 0.57 | POLB (0.44) | GAA | |
| SCHEMBL4094120 | 0.56 | HDAC1 (0.45) | KDM4E | |
| SCHEMBL11139095 | 0.56 | EGLN1 (0.47) | ALDH1A1KDM4EHPGD | |
| SCHEMBL366720 | 0.56 | EGLN1 (0.47) | ALDH1A1KDM4EHPGD | |
| SCHEMBL10886941 | 0.56 | HRH1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193377-A1 | Radiolabeled Nanohybrids Targeting Solid Tumor Neovasculature and Method of Using Same | UNIVERSITY OF MARYLAND, BALTIMORE | 2008-08-14 | — | — | US | disclosed |
| EP-1768706-A2 | RADIOLABELED NANOHYBRIDS TARGETING SOLID TUMOR NEOVASCULATURE AND METHOD OF USING SAME | University of Maryland, Baltimore (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006012355-A2 | RADIOLABELED NANOHYBRIDS TARGETING SOLID TUMOR NEOVASCULATURE AND METHOD OF USING SAME | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2006-02-02 | — | — | WO | disclosed |