Fenpentadiol

Fenpentadiol

SCHEMBL48969

CC(C)(O)CC(C)(O)c1ccc(Cl)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.58
MEN1 O00255 5/20 0.58
NPSR1 Q6W5P4 2/20 0.48
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
BCL2 P10415 1/20 0.42
CYP19A1 P11511 3/20 0.41
POLB P06746 2/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MIF P14174 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906164 0.80 KMT2A (0.60) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL6480252 0.80 KMT2A (0.60) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL12224193 0.80 KMT2A (0.60) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL23795276 0.79 KMT2A (0.51) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL23795282 0.79 KMT2A (0.51) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL10253668 0.78 KMT2A (0.58) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL22395252 0.78 KMT2A (0.58) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL12352042 0.78 KMT2A (0.58) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL15759500 0.78 KMT2A (0.58) KMT2AMEN1NPSR1TSHRMAPK1
SCHEMBL22623891 0.77 KMT2A (0.56) KMT2AMEN1NPSR1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1027 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11534375-B2 Solvent-free method of encapsulating a hydrophobic active AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-12-27 US claimed
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP claimed
US-20200179248-A1 SOLVENT-FREE METHOD OF ENCAPSULATING A HYDROPHOBIC ACTIVE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-06-11 US claimed
WO-2018182509-A1 SOLVENT-FREE METHOD OF ENCAPSULATING A HYDROPHOBIC ACTIVE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-10-04 WO claimed
US-9757376-B2 Pharmaceutical compositions GM PHARMACEUTICALS, INC. (US) 2017-09-12 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-2560634-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS Piramal Enterprises Limited (IN) 2013-02-27 EP claimed
EP-2007394-B1 NOVEL USE OF ANTIHISTAMINE AGENTS FOR THE PREVENTIVE OR EARLY TREATMENT OF INFLAMMATORY SYNDROMES, IN PARTICULAR THOSE TRIGGERED BY TOGAVIRUSES PF MEDICAMENT (FR) 2012-10-10 EP claimed
WO-2012116278-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. (US) 2012-08-30 WO claimed
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 US claimed
EP-1641446-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF Pediamed Pharmaceuticals, Inc. (US) 2006-04-05 EP claimed
WO-2005084654-A2 METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PSYCHIATRIC DISORDERS WITH COX-2 INHIBITORS ALONE AND IN COMBINATION WITH ANTIDEPRESSANT AGENTS PHARMACIA CORPORATION (US) 2005-09-15 WO claimed
WO-2004112771-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF PEDIAMED PHARMACEUTICALS, INC. (US) 2004-12-29 WO claimed
US-20040259809-A1 Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof PEDIAMED PHARMACEUTICALS, INC. 2004-12-23 US claimed
EP-0687172-B1 SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF PHARMACIA AB (SE) 2002-12-04 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
US-6207178-B1 STABLE SUSPENSION KABI PHARMACIA AB (SE) 2001-03-27 US claimed
US-5785976-A Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof PHARMACIA & UPJOHN AB (SE) 1998-07-28 US claimed
EP-0687172-A1 SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF Pharmacia & Upjohn Aktiebolag (SE) 1995-12-20 EP claimed
WO-1994020072-A1 SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF PHARMACIA AB (SE) 1994-09-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents NOS2, NOS1, NOS3 KMT2A 3867/4885MEN1 2829/4885NPSR1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.