Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 3/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507953 | 0.83 | PDE4A (0.39) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL15643165 | 0.78 | MGAM (0.36) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL15563004 | 0.76 | PDE4A (0.56) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| Mannitol SCHEMBL29233680 | 0.76 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL10753257 | 0.76 | PDE4A (0.56) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| Mannitol SCHEMBL31109182 | 0.75 | PDE4A (0.58) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL21045764 | 0.75 | CA2 (0.35) | TDP1 | |
| SCHEMBL2933990 | 0.75 | PDE4A (0.54) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL8465610 | 0.75 | PDE4A (0.54) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL8492543 | 0.75 | USP2 (0.55) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139500-A1 | Use of composite monomer or monomers, catalyst, sodium hyaluronate or hyaluronic acid, glucosamide sulfate, chondroiten sulfate or chlorides, for the treatment of osteoarthritis by intraarticular application to a hip or knee joint | GOLDBERG ISADORE ELLIOTT | 2008-06-12 | — | — | US | disclosed |