Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896921 | 0.83 | PDE4A (0.48) | PDE4ALMNAUSP2SLCO1B1MGAM | |
| SCHEMBL15643165 | 0.80 | MGAM (0.36) | PDE4ALMNAUSP2SLCO1B1MGAM | |
| SCHEMBL378867 | 0.71 | PDE4A (0.61) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Mannitol SCHEMBL29233680 | 0.71 | PDE4A (0.50) | PDE4ALMNAUSP2SLCO1B1MGAM | |
| SCHEMBL7132995 | 0.71 | PDE4A (0.61) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL28066668 | 0.71 | PDE4A (0.61) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Mannitol SCHEMBL31109182 | 0.70 | PDE4A (0.58) | PDE4ALMNAUSP2SLCO1B1MGAM | |
| SCHEMBL6234202 | 0.70 | PDE4A (0.59) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL9576619 | 0.70 | PDE4A (0.59) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL7590412 | 0.70 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289970-B1 | Biocompatible polymers | BARRITAULT DENIS (FR) | 2015-05-20 | — | — | EP | disclosed |
| EP-1117695-B1 | BIOCOMPATIBLE POLYMERS, COMPOSITIONS CONTAINING SAME AND THEIR USE FOR THE MANUFACTURE OF DRUGS | BARRITAULT DENIS (FR) | 2015-05-20 | — | — | EP | disclosed |
| EP-2289970-A1 | Biocompatible polymers, their process of manufacture and compositions containing them | Barritault, Denis (FR) | 2011-03-02 | — | — | EP | disclosed |
| EP-1117695-A1 | BIOCOMPATIBLE POLYMERS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Barritault, Denis (FR) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000005270-A1 | BIOCOMPATIBLE POLYMERS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | BARRITAULT DENIS (FR) | 2000-02-03 | — | — | WO | disclosed |